TORCH 10 Profile Test
TORCH 10 Profile Test
The TORCH 10 Profile is a diagnostic panel designed to screen for infections that can significantly impact pregnancy outcomes and neonatal health. It measures Immunoglobulin G (IgG) and Immunoglobulin M (IgM) antibodies against a group of infectious agents collectively referred to as TORCH. These agents include Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), and Herpes simplex viruses (HSV-1 and HSV-2). Early detection and intervention can prevent complications such as congenital anomalies, miscarriage, or stillbirth.
What is the TORCH 10 Profile Used For?
The TORCH 10 Profile is a comprehensive test primarily used to:
- Detect Active Infections During Pregnancy: Identifies infections that may be passed from mother to baby, helping to manage risks and ensure better outcomes.
- Diagnose Congenital Infections in Newborns: Useful for identifying infections in babies who present with symptoms like jaundice, neurological abnormalities, or developmental delays.
- Assess Immunity in Women Planning Pregnancy: Determines if an individual has immunity to infections that could potentially harm a pregnancy.
- Investigate Recurrent Pregnancy Loss: Evaluates whether infections are contributing factors to repeated miscarriages or complications.
What does the TORCH 10 measure?
This profile specifically measures IgG and IgM antibodies against the following agents
Toxoplasma gondii
-
A parasitic infection that can cause severe complications in the fetus, including brain damage and vision problems.
Rubella virus
-
Responsible for congenital rubella syndrome, leading to heart defects, hearing impairment, and developmental delays.
Cytomegalovirus (CMV)
-
A common viral infection that can cause hearing loss and intellectual disabilities in newborns.
Herpes simplex virus 1 (HSV-1) and Herpes simplex virus 2 (HSV-2)
-
- Can lead to severe neonatal infections if transmitted during delivery.
Who Should Get Tested?
The TORCH 10 Profile may be recommended under the following circumstances
Pregnant Women with symptoms such as fever, rash, swollen lymph nodes, or a history of miscarriage
Newborns who present with signs like jaundice, low birth weight, seizures, or developmental abnormalities
For women planning to conceive, particularly if they have no documented immunity to TORCH infections.
Preparation for the Test
The TORCH 10 Profile involves a simple blood test. Here are steps to prepare for accurate results:
- No Fasting Required: You can eat and drink as usual before the test.
- Discuss Medications: Inform your healthcare provider about any ongoing medications or supplements that could influence antibody levels.
- Optimal Timing: If exposure to an infection is suspected, testing should occur within a specific timeframe to detect IgM antibodies effectively.
Interpretation of Results
The test results include IgM and IgG antibody measurements for each infection. These antibodies indicate different stages of infection:
- IgM Antibodies: Suggest a recent or active infection.
- IgG Antibodies: Indicate past exposure or immunity.
Key Interpretations:
- Positive IgM, Negative IgG: Indicates an active or recent infection that requires immediate attention.
- Positive IgG, Negative IgM: Suggests past infection or immunity, usually reassuring.
- Positive IgM and IgG: Recent infection; may necessitate further testing to confirm timing and evaluate risks.
- Negative IgM and IgG: No evidence of infection or immunity, indicating susceptibility.
Results are reviewed in conjunction with clinical history and symptoms to guide management and treatment.
FAQs
Related tests
Tests At Lupin Diagnostics