Serum Total Protein Test: Booking, Price, and Results
About Serum Total Protein Test: Booking, Price, and Results
| Field | Value |
|---|---|
| Also Known As | Total serum protein, TP, Serum protein, Protein total |
| Sample Type | Venous blood (serum) |
| Fasting Required | Not needed, however your doctor may recommend fasting if other tests are being done alongside the protein test |
| Report Time | Same day or within 24 hours |
| Recommended For | All individuals, especially those with kidney or liver disorders |
| Price | Starting at ₹190 |
What Is a Serum Total Protein Test?
The serum total protein test measures the total amount of protein circulating in your blood. It looks at two main protein groups: albumin and globulins. Doctors order this test to get a broad picture of your liver and kidney function, as well as your nutritional health. A venous blood sample from your arm is all that is needed.
What Does a Serum Total Protein Test Measure?
The total protein test analyses four key values in your blood. Here is what each one tells your doctor:
| Parameter | What It Represents |
|---|---|
| Total Protein | The combined amount of albumin and globulin in the blood; reflects general health status |
| Albumin | A protein made by the liver that keeps fluid within blood vessels and carries hormones, vitamins, and medicines through the body |
| Globulins | A group of proteins that includes carrier proteins, enzymes, and immunoglobulins (antibodies); most are produced by the liver, while immunoglobulins come from immune cells |
| A/G Ratio (Albumin-to-Globulin Ratio) | The balance between albumin and globulin levels; helps identify liver, kidney, or immune system issues |
Why Is a Serum Total Protein Test Done?
This test is ordered for several reasons, ranging from routine health screening to investigating specific symptoms.
Common Symptoms That May Require This Test
Your doctor may request a total protein test if you are experiencing any of the following:
- Unexplained fatigue or persistent weakness
- Unexpected weight loss
- Swelling in the feet, ankles, or abdomen (oedema)
- Jaundice (yellowing of the skin or whites of the eyes)
- Abdominal bloating or discomfort
- Frequent infections
- General decline in health with no clear cause
Conditions This Test Can Help Detect
The serum total protein test can help identify a range of conditions, including:
- Liver disease, such as cirrhosis or viral hepatitis.
- Kidney disease, including nephrotic syndrome.
- Nutritional deficiencies or malabsorption disorders.
- Bone marrow disorders, such as multiple myeloma or Waldenström macroglobulinaemia.
- Autoimmune conditions and immune deficiency states.
- Chronic inflammation.
Serum Total Protein Test for Chronic Disease Monitoring
For people already diagnosed with liver or kidney disease, multiple myeloma, or nutritional disorders, doctors may request a total protein test at regular intervals. Tracking protein levels over time helps assess how well a condition is responding to management and whether it is progressing. It is also used to monitor nutritional status in patients with digestive disorders.
How to Prepare and What to Expect
No complex preparation is needed before a serum total protein test. Here is what you should know before your appointment.
Do You Need to Fast?
No, fasting is not required for this test. You can eat and drink normally before your blood draw. If your doctor has ordered additional tests alongside this one, some of those may require fasting, so check with your doctor or the laboratory in advance.
Practical Tips Before Your Test
A few simple steps can help ensure a smooth experience:
- Tell your doctor about all medicines and supplements you take, particularly steroids, immunosuppressants, or hormone therapy.
- Drink enough water before your appointment; good hydration makes veins easier to access.
- Avoid intense exercise immediately before the test.
- Wear a short-sleeved or loose-fitting top for easy access to your arm for sample collection.
Step-by-Step Procedure
The blood collection process is straightforward and quick. Here is what happens at the collection centre or during a home visit:
- A trained phlebotomist cleans the inside of your elbow with an antiseptic wipe.
- A fine needle is gently inserted into a vein, and a small amount of blood is drawn into a collection tube.
- Light pressure is applied to the puncture site to stop any bleeding.
- A small bandage is placed on the site, and the sample is labelled and sent to the laboratory for analysis.
Factors That Can Affect Accuracy
Certain factors may influence your total protein test result:
- Recent infections or ongoing inflammation.
- Medications such as steroids, immunosuppressants, or hormones.
- Intravenous fluids given before the test.
- Dehydration (can falsely raise protein levels) or overhydration (can lower them).
Understanding Your Serum Total Protein Test Results
Your results show the levels of each protein fraction in your blood. A doctor must review these values alongside your symptoms, medical history, and other test findings to reach any conclusion. The table below shows the general reference ranges:
| Parameter | Normal Range | Unit |
|---|---|---|
| Total Protein | 6.0 to 8.3 | g/dL |
| Albumin | 3.5 to 5.5 | g/dL |
| Globulin | 2.0 to 3.5 | g/dL |
| A/G Ratio | 1.0 to 2.0 | — |
These ranges are general guidelines. Your doctor will interpret your results based on your age, health history, and other factors. Always consult a qualified healthcare professional for personalised medical advice.
Results During Special Conditions
Some circumstances can alter how results are read:
- During pregnancy, blood volume increases by roughly 40 to 50%, which dilutes the concentration of proteins in the blood. Lower total protein test results during pregnancy generally reflect this dilution rather than a problem with the liver or nutrition.
- Prolonged bed rest can also alter protein levels.
- Similarly, severe dehydration may cause results to appear falsely elevated, while intravenous fluids given before the test may produce lower readings.
How to Maintain Healthy Levels
These general tips support healthy protein balance in the body:
- Include protein-rich foods in your daily diet, such as lentils, chickpeas, eggs, dairy products, lean meats, and fish.
- Support liver health by limiting alcohol intake and choosing nutritious, balanced meals.
- Stay well hydrated throughout the day by drinking sufficient water.
Lupin Diagnostics Serum Total Protein Test Price and Home Collection
The serum total protein test is available at Lupin Diagnostics with home sample collection across major Indian cities. Indicative prices based on aggregator data are listed below:
| City | Approximate Price (₹) |
|---|---|
| Bengaluru | ₹220 |
| Chennai | ₹250 |
| Hyderabad | ₹260 |
| Kolkata | ₹190 |
| Pune | ₹250 |
| Guwahati | ₹190 |
Prices are indicative and may vary by location. Please confirm the current price at the time of booking.
How to Book
Follow these steps to book your total protein test online or at a centre:
- Select the test on the Lupin Diagnostics website.
- Choose your city and preferred time slot.
- Opt for home sample collection by a certified phlebotomist, or visit your nearest Lupin Diagnostics centre.
- Receive your report via email or WhatsApp within the stipulated turnaround time.
Home Collection
Lupin Diagnostics offers home collection for the serum total protein test across cities, so you can get tested without visiting a centre. All samples are processed in NABL-accredited laboratories by experienced professionals. Your digital report is delivered directly to you via email or WhatsApp.
Frequently Asked Questions
The serum total protein test is used to check how well your liver and kidneys are functioning and to assess your nutritional status. Doctors also use it to investigate symptoms such as swelling, fatigue, or unexplained weight loss and to screen for conditions affecting protein levels in the blood.
No fasting is needed. You can eat and drink as usual before your appointment. If you are having additional blood tests on the same day, your doctor will advise you if fasting is required for any of those.
Levels outside the normal range may point to conditions affecting the liver, kidneys, immune system, or nutritional intake. High levels can be linked to dehydration, chronic infection, or bone marrow disorders. Low levels may suggest liver disease, kidney disease, or malnutrition. Your doctor will interpret any abnormal total protein test result in the context of your full health picture.
Yes, it is frequently included in a comprehensive metabolic panel (CMP), a standard blood panel that checks proteins and other substances in the blood. Many routine health packages include this test as part of a broader screen.
The A/G ratio compares your albumin level to your globulin level. A low ratio may suggest liver or kidney disease, while a high ratio can indicate chronic inflammation or autoimmune conditions. It gives doctors additional context beyond the total protein figure alone.
Yes. Medicines such as steroids, immunosuppressants, and hormone therapies can alter protein levels in the blood. Always tell your doctor about any medicines or supplements you take before undergoing a total protein test.
For most healthy adults, this test is done once a year as part of a routine check-up or metabolic panel. People managing chronic liver disease, kidney disease, or immune conditions may need it more frequently, as directed by their doctor.








