HSV-1 IgG Antibody
HSV-1 IgG Antibody
Herpes simplex virus causes herpes infection. It is of two types – oral herpes (which causes cold sores around the mouth or face), and genital herpes (which affects the genitals, anal areas, and buttocks region). It is spread through direct contact from an infected individual to others. When infected, the body’s immune system will produce antibodies (proteins that help fight against infection) specific to herpes infection.
Herpes Simplex Virus (HSV) IgG antibody test is used to determine IgG antibodies that help diagnose herpes infection in an individual. The HSV-1 IgG Antibody test is used to screen for both active and recurrent Herpes simplex virus infection in individuals. These IgG antibodies are usually found in the blood after three to four weeks of initial infection by the virus
What is HSV-1 IgG antibody test used for?
The HSV-1 IgG antibody test is recommended in individuals when:
· Repeated symptoms are shown with a negative test result but active herpes infection
· Risk exposure to herpes virus with no symptoms
· Expecting a child or attempting to conceive
· HIV positive or at high risk of contracting it
Symptoms of Herpes infection
Mostly the herpes infection is asymptomatic, i.e., with no symptoms. However, if symptoms appear they include
Open sores (ulcers) – characteristic feature of herpes infection
Fever
Body aches
Sore throat (oral herpes
Headache
Swollen lymph nodes
Who should get tested?
The HSV-1 test should be taken by individuals who are:
Sexually active
Have more than one sexual partner
Have sex with partners affected with herpes or other STDs
Trying to conceive or pregnant
Test preparation
No special preparation is required to take HSV-1 IgG antibody test.
Please talk to your healthcare provider if you are on any medications before taking the test.
Interpretation of the Test Results
Normal ranges: 0.90 – 1.09 IV (intravenous immunoglobulins)
The test results for herpes simplex virus – 1 IgG antibody test are given as either positive or negative.
Positive test results – It indicates there were IgM antibodies detected in the individual’s blood and may mean one of the following two things:
1. Active or current infection
2. Past infection
Negative test results – It indicates there were no IgG antibodies found in the individual’s blood sample and it is likely that the individual is not infected with the herpes simplex virus
FAQs
What is the turnaround time (TAT) for HSV-1 IgG antibody test?
The test results for HSV-1 IgG antibody test are generally available within 2 – 3 working days after the sample collection. However, it can also take a little longer at times
Are there any risks related to HSV-1 IgG Antibody test?
No, there are no potential risks associated with HSV-1 IgG antibody test. It is a simple blood test and may involve negligible risk such as feeling a slight sting or bruise at the site of needle insertion. It usually resolves within a few minutes to a couple of hours. Rarely, the site can become infected
What is the test procedure involved in HSV-1 IgG antibody test?
Your healthcare professional will draw a few millilitres of blood from you by inserting a small needle into a vein in your arm. You may be instructed to make a fist to make your veins more visible for easier collection of blood
Can I get false-negative results for HSV-1 IgG antibody test?
Yes, false-negative test results are possible if you take this test before the window period for IgG antibody formation. After the first infection, it takes about 3 - 6 weeks for the production IgG antibodies. Any tests performed prior to this time may yield false-negative findings
How long do herpes IgG antibodies remain positive?
Once infected with the herpes simplex virus, it takes between 20 - 40 days for the immune system to release antibodies in the body. Once released, these remain positive for the rest of one's life
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