HCV RNA Qualitative by PCR
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About HCV RNA Qualitative by PCR
Hepatitis C is a contagious blood-borne viral infection that affects the liver. It spreads through infected blood and often has no symptoms for decades. When left untreated, it progresses to serious life-threatening conditions such as cirrhosis, fibrosis, cancer and even death.
HCV RNA Qualitative assay, based on polymerase chain reaction (PCR), is an important diagnostic tool to help doctors detect the presence or absence of HCV genetic material (RNA) in the patient’s blood sample.
Typically, this test follows positive anti-HCV antibody test results for more than 6 months to indicate that the patient has progressed to chronic hepatitis C. However, it cannot quantify the virus in the body.
For most qualitative HCV RNA assays, the lower limit for detecting the virus is 10-15 IU/mL
What is HCV RNA Qualitative PCR Used For?
The HCV RNA qualitative PCR test is used:
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To confirm a positive HCV antibody screening result and make the diagnosis of chronic HCV infection
Symptoms of Hepatitis C
Most people with HCV lack symptoms. Yet, a small percentage may experience mild symptoms such as:
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Jaundice (yellow discoloration of the eye and skin)
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Tiredness
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Nausea and Vomiting
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Fever
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Pain in the upper right part of the belly
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Joint pain
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Dark-colored urine and stool
Test preparation
This test does not require any preparation. However, let your doctor know the medications and supplements you're currently taking to avoid interference with test results
Interpretation of the Test Results
Positive result (Detected)
This result indicates the presence of viral RNA in the blood and confirms the patient has chronic hepatitis C. Your doctor will assign the patient for an HCV RNA quantitative test to determine the viral load in the body
Negative result (Not Detected)
This result suggests no sign of virus in the blood
FAQs on HCV RNA PCR Quantitative, Real-Time PCR
Yes, this test is almost accurate in detecting an HCV infection within 1–2 weeks after exposure, regardless of how low the viral load is in the blood
Individuals with risk factors for HCV exposure such as a history of injection drug use, blood transfusion, HIV infection, hemophilia, or those undergoing hemodialysis should get tested
More than half of individuals exposed to hepatitis C eventually develop chronic infection
According to CDC recommendations, women should be tested for hepatitis C during every pregnancy, and if positive, their babies should also be tested within two months after birth
HCV RNA PCR Quantitative, Real-Time PCR
