DNA Extraction and Storage Test: Booking, Price, and Results
About DNA Extraction and Storage Test: Booking, Price, and Results
| Field | Value |
|---|---|
| Also Known As | DNA Banking, DNA Preservation, DNA Extract and Hold, Genomic DNA Storage |
| Sample Type | Chorionic Villus (CVS), Amniotic Fluid, Cord Blood, Whole Blood, Products of Conception |
| Fasting Required | No |
| Report Time | 3 days |
| Recommended For | All genders, all ages (including neonates and infants in specific clinical scenarios) |
| Price | Starting at ₹1,200 |
What is a DNA Extraction and Storage Test?
The DNA extraction and storage test is a clinical laboratory service that isolates your genetic material (DNA) from a biological sample and preserves it securely for future use. It is also referred to as DNA banking or DNA preservation. A doctor or genetic counsellor typically recommends this service when there is a need to retain genetic material for possible future testing. Accepted samples include chorionic villus (CVS), amniotic fluid, cord blood, whole blood, and products of conception.
What Does a DNA Extraction and Storage Test Measure?
This is not a conventional diagnostic test that reports health values. Instead, the laboratory carries out the following steps and confirms their success.
Here is what the process involves and what the laboratory documents:
| Parameter | What It Means |
|---|---|
| DNA yield | The quantity of DNA obtained from the submitted sample |
| DNA purity (A260/A280 ratio) | A measure of DNA quality; an acceptable value is approximately 1.8, indicating clean DNA free of protein contamination |
| DNA integrity | Confirms the DNA is intact and of high molecular weight, suitable for future genetic testing |
The laboratory report confirms successful extraction along with the concentration and quality of the stored DNA, rather than disease-related values.
Why is a DNA Extraction and Storage Test Done?
This service is ordered for preservation and planning purposes across a range of clinical and personal situations. Below are the key reasons a doctor or genetic counsellor may recommend it.
Common Reasons This Test May Be Requested
The following situations commonly lead to a DNA extraction and storage test being ordered:
- Suspected hereditary condition where current testing options are limited
- Family history of a known genetic disorder
- End-of-life or perimortem planning, where preserving DNA allows future molecular investigation
- Unexplained deaths, including sudden infant death, sudden cardiac events, or fetal demise
- Evaluation of cancer susceptibility in individuals with a relevant family history
- Future paternity or biological relationship testing
- Participation in genetic research studies
Conditions This Test Can Help Address
Once the DNA is stored, it can be used in the future to support testing related to the following:
- Hereditary genetic disorders
- Inherited cardiac conditions
- Cancer predisposition syndromes
- Undiagnosed rare diseases
- Forensic or legal identification requirements
How to Prepare and What to Expect
No fasting or significant preparation is needed for the DNA extraction and storage test procedure. The following subsections cover what you should know before and during the process.
Do You Need to Fast?
No fasting is required. This service has no dietary restrictions before sample collection.
Practical Tips Before Your Test
Keep the following points in mind before your appointment:
- Bring a detailed clinical history record, including your symptoms, previous test results, and family history, as this is required for the test
- Inform the healthcare professional about any recent blood transfusions or known blood disorders, as these may affect DNA quality
- Complete any consent forms before the appointment, as DNA banking involves long-term storage of personal genetic material
- Speak with your doctor or a genetic counsellor about the purpose of storing your DNA and what future tests may be performed on it
Step-by-Step Procedure
The collection procedure varies depending on the type of sample submitted. Below is a description of each accepted sample type.
Whole Blood:
- A healthcare professional draws a blood sample from a vein, usually in the arm, into a sterile collection tube
- The sample is labelled and stored at 2 to 8°C for transport to the laboratory
- In the laboratory, DNA is isolated from white blood cells using validated automated extraction methods
- The extracted DNA is measured for quantity and purity
- The DNA is then stored under controlled temperature conditions for future use
Chorionic Villus (CVS), Amniotic Fluid, Cord Blood, and Products of Conception:
- These samples are collected by a qualified specialist in a clinical setting using sterile procedures appropriate to each sample type
- The collected material is placed in a sterile container and stored at 2 to 8°C during transit to the laboratory
- DNA is extracted from the relevant cells in the sample using automated laboratory methods
- The extracted DNA is assessed for yield, purity, and integrity
- Confirmed high-quality DNA is then stored securely for future genetic testing
- The laboratory issues a report confirming successful extraction and documenting the storage conditions
Factors That Can Affect Accuracy
The following factors may affect the quality of extracted DNA:
- Delay between sample collection and laboratory processing (DNA should ideally be processed within 3 days of collection at room temperature)
- Improper storage or transport temperature
- Exposure to heat, sunlight, or contaminants before processing
- Use of an incorrect collection tube (EDTA tubes are preferred over heparin tubes for blood)
- Recent blood transfusion, which may introduce donor DNA into the sample
- Very low white blood cell count (leucopenia), which may reduce DNA yield from blood
Understanding Your DNA Extraction and Storage Test Results
The DNA extraction and storage test does not produce clinical reference ranges in the traditional sense. Your report will confirm whether DNA was successfully extracted and stored. Always review the report with your doctor or genetic counsellor.
| Parameter | Acceptable Outcome |
|---|---|
| DNA yield | Adequate for downstream genetic testing |
| DNA purity (A260/A280 ratio) | Approximately 1.8 |
| DNA integrity | Intact, high molecular weight confirmed |
Disclaimer: These are laboratory quality parameters, not patient health values. Your doctor will interpret the report in the context of your clinical history and advise on any further steps. Always consult a qualified healthcare professional for personalised medical advice.
Results During Special Conditions
Certain individual circumstances may affect the quality of the extracted DNA:
- A recent blood transfusion may introduce donor DNA, which can compromise the purity of the individual's genetic material from a blood sample
- Haematological malignancies (blood cancers) may affect the quality of DNA extracted from blood
- Severely low white blood cell counts may reduce the DNA yield obtained from a blood sample
How to Maintain Healthy Levels
Since this is a preservation service rather than a diagnostic test, the following tips focus on supporting sample quality and the integrity of stored DNA:
- Stay well hydrated before sample collection, as this can support an easier blood draw if whole blood is the chosen sample type
- Avoid strenuous physical activity immediately before collection
- Discuss with the laboratory how long your DNA will be stored and what future tests can be carried out on it
Lupin Diagnostics DNA Extraction and Storage Test Price
The DNA extraction and storage test cost at Lupin Diagnostics starts at ₹1,200. This test requires a visit to a Lupin Diagnostics centre, as home collection is not available for this service.
| City | Approximate Price (₹) |
|---|---|
| BHOPAL | 1200 |
| CHENNAI | 1200 |
| HYDERABAD | 1200 |
| KOLKATA | 1200 |
| NAVI MUMBAI | 1200 |
| PUNE | 1200 |
Disclaimer: Prices are indicative and may vary by location. Please confirm the current price at the time of booking.
How to Book
Follow these steps to get your DNA extraction and storage test online booking:
- Select the test on the Lupin Diagnostics website.
- Choose your city and preferred centre location.
- Visit the centre at your scheduled time for sample collection by a trained healthcare professional.
- Receive your report via email or WhatsApp within the stipulated turnaround time.
Frequently Asked Questions
It is a clinical laboratory service in which DNA (your genetic material) is isolated from a biological sample and securely preserved for future genetic testing. It is also called DNA banking or DNA preservation. It is not a diagnostic test that produces health-related values.
This service is useful for individuals with a suspected hereditary condition, a family history of genetic disease, or those undergoing end-of-life planning. It is also relevant in situations involving unexplained deaths, where preserving DNA allows future investigation for surviving family members.
Lupin Diagnostics accepts chorionic villus (CVS), amniotic fluid, cord blood, whole blood, and products of conception for the DNA extraction and storage test. The appropriate sample type depends on your clinical situation and will be guided by your doctor.
No fasting is required. You should bring a detailed clinical history to your appointment, as this is required for the test. Inform the healthcare professional about any recent blood transfusions or blood disorders before sample collection.
When stored under the right conditions, extracted DNA can remain stable for several years. Some facilities store DNA for 15 years or longer under appropriate frozen conditions. Discuss storage duration and terms with the laboratory at the time of banking.
No. This is a preservation service, not a diagnostic test. The stored DNA can later be used for specific genetic tests that may help assess hereditary conditions, cancer risk, or biological relationships, but extraction and storage alone do not produce a diagnosis.
Yes. As the depositor, you retain ownership of the stored sample. You may request that the DNA be tested further, withdrawn, transferred to another facility, or destroyed. Confirm the specific terms of storage and access with the laboratory at the time of banking.
DNA Extraction and Storage Test: Booking, Price, and Results
