Dihydrotestosterone (DHT)
Dihydrotestosterone (DHT)
The DHT test is used to measure the concentrations of the dihydrotestosterone hormone in the blood sample. This hormone is produced by the reduction of testosterone by 5-alpha reductase. DHT plays an important role in the formation of masculine characteristics such as facial hair, a deep voice, and the development of male reproductive organs. Abnormal DHT levels can lead to various complications based on one's age and sexual development stage. Thus, it is recommended to undergo this test to aid in the diagnosis of various conditions, including prostate cancer, polycystic ovary syndrome (PCOS), etc.
Symptoms of abnormal DHT levels
Low sex drive
Hair loss
Acne
Enlarged prostate gland
Mood swings
Increased facial and body hair
Irregular periods
What is the Dihydrotestosterone (DHT) test used for?
The DHT test is recommended
To evaluate patients with possible 5-alpha reductase deficiency
To monitor patients receiving 5-alpha reductase inhibitor therapy or chemotherapy
Preparation for the test
No special preparation is required for this test. Some medications might affect the test results, so be sure your healthcare provider is aware of any prescription drugs, over-the-counter medicines, or dietary supplements you are taking.
Interpretation of results
The reference ranges for the DHT test may vary based on age, gender, and from lab to lab. The normal reference ranges are given in nanograms per decilitre (ng/ dL).
Â
|
Parameters |
Reference range (males) |
Reference range (females) |
|
DHT |
30-85 ng/dL |
4–22 ng/dL |
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Deviation from normal results indicates the following:
·        Elevated levels of DHT may be caused due to prostate cancer, idiopathic hirsutism (presence of coarse hairs), and polycystic ovary syndrome (PCOS).
·        Low levels of DHT may be caused due to Klinefelter's syndrome (extra copy of the X chromosome), azoospermia (no sperm in the ejaculate), and anorchia (absence of both testes at birth).
FAQs
How is the sample collected for the DHT test?
A healthcare provider will draw a small blood sample from a vein in your arm using a needle. The blood will be collected in a test tube or vial and sent to the lab for analysis.
What are the risks associated with the DHT test?
There are no known risks associated with this test. During a blood test, one may experience minor pain or bruising where the needle was inserted, but most symptoms will subside quickly.
What is the turnaround time (TAT) for the result of the DHT test?
The DHT test result is usually available within 1-5 working days after the sample collection. This duration may vary depending on the particular diagnostic clinic.
What factors might affect my DHT test results?
Several factors, such as age, gender, genetic predisposition, and the use of medications like testosterone replacement therapy or certain hair loss treatments, may impact DHT levels.
What happens if I receive an abnormal DHT test result?
If you receive an abnormal DHT test result, it is important to consult with a urologist or endocrinologist for further evaluation and guidance. Your healthcare provider will be able to interpret the results and may recommend additional tests to determine the underlying cause of the hormonal imbalance. Once a diagnosis is reached, an appropriate treatment plan will be implemented.
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