Cytomegalovirus (CMV) IgG & IgM
Cytomegalovirus (CMV) IgG & IgM
The CMV IgG & IgM test detects antibodies in the blood that are produced in response to a CMV infection. This test can be used to diagnose a current or past infection by measuring and identifying two classes of CMV antibodies (IgG and IgM).
Transmission of CMV can occur when handling or coming into contact with bodily fluids, such as saliva, blood, urine, breast milk, and semen. Typically, the virus leads to a mild illness; however, it can have severe consequences for unborn children, individuals with HIV/AIDS, or those with weakened immune systems. Antibodies, which are produced by the immune system in response to infection, serve as germ-fighting molecules. If CMV-specific antibodies are present in your blood, it may indicate a CMV infection. Thus, getting this test is recommended to help in the early detection and diagnosis of cytomegalovirus infection and prevent its related complications
Symptoms of CMV infection
Prolonged high fever
Fatigue
Loss of appetite
Muscle pain
Joint pain or stiffness
Headache
Sore throat
Swollen lymph nodes
Enlarged liver and spleen
Who should get tested?
CMV, IgG & IgM test is recommended for the following individuals and conditions:
Testing for the CMV virus in the blood to confirm that an infection is the cause of an individual’s symptoms
Individuals with weakened immune systems due to certain infections or diseases
Pregnant women with symptoms of a CMV infection
People who have recently received an organ transplant
Newborns with symptoms of infection
Test preparation
No special preparation is required for the CMV IgG & IgM test.
Interpretation of the Test Results
Interpretation of the test results
· In the presence of symptoms, a positive result for both CMV IgG and IgM indicates a likelihood of recent exposure to CMV for the first time or reactivation of a previous CMV infection.
· A positive result for CMV IgM and a negative result for IgG indicates a possible recent infection.
· A negative result for CMV IgM and a positive result for IgG indicates a possible previous exposure (immunity to primary infection).
A negative result for both CMV IgG and IgM indicates no current or prior infection, and the symptoms are not due to CMV infection
FAQs
How is the sample collected for the CMV IgG & IgM test?
For the CMV IgG & IgM test, a healthcare professional will take a small amount of blood from a vein in your arm using a small needle, which is collected in a test tube or vial. The collected sample is then sent to a laboratory for further analysis
What are the risks associated with the CMV IgG & IgM test?
There are no known risks associated with this test. During a blood test, one may experience minor pain or bruising where the needle was inserted, but most symptoms will subside quickly
What is the turnaround time (TAT) of the CMV IgG & IgM test?
The test results are usually available within 3-4 working days after the sample collection. This duration may vary depending on the diagnostic clinic
What are the indicators of a reactivated cytomegalovirus (CMV) in the body?
Healthy individuals will probably not have a symptomatic reactivation or may experience mild flu-like symptoms. However, immune-compromised individuals may face more serious symptoms that affect their lungs, digestive tract, or eyes. In such cases, it is important to consult the healthcare provider regarding any health concerns
How often should I be tested for CMV antibodies?
The frequency of testing is determined by your health condition and the presence of risk factors. Pregnant women and individuals with compromised immune systems may require testing at more regular intervals
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