CUSTOM IHC PANEL TEST
A custom Immunohistochemistry (IHC) panel test is a diagnostic technique crucial for cancer detection and identifying specific antibodies binding to cell surface antigens. This specialized staining method targets molecules serving as markers distinguishing between benign and malignant tumours. Predominantly utilized in oncology, IHC plays a pivotal role in cancer diagnosis by highlighting distinctive molecular patterns indicative of tumour behaviour. Your healthcare provider may order this panel to diagnose and manage certain cancers.
What is custom IHC panel used for?
Custom IHC panel is done to:
Find out if the cancer has spread to other parts of the body (metastasis)
Predict how fast the cancer cells may grow
Select the right cancer treatment
Monitor how well the treatment is working
See if there is a recurrence of cancer even after treatment
Identify the stage and the grade of the tumour
Preparation for the test
No special preparation is required for a custom IHC panel.
Interpretation of results
Abnormal or positive test results
Abnormal or positive test results indicate the presence of a marker or receptor on the cell during biopsy or denote a specific alteration in the tumour's protein. A positive result suggests the possibility that the person may have inherited a genetic condition.
Negative test results
Negative test results indicate that the laboratory did not detect any alterations in the protein or cell markers. This suggests that the individual is neither affected by the cancer, is not a carrier of a particular genetic mutation, nor has an elevated risk of developing cancer or related disease.
FAQs
How is the sample collected for the custom IHC panel?
For a custom IHC panel, tissue samples are typically collected through biopsy or surgery. Following collection, tissues are fixed, embedded in paraffin, and sliced into thin sections. These sections are then mounted on slides for staining with specific antibodies tailored to the desired protein targets for analysis.
What are the risks associated with the custom IHC panel?
There are no known risks associated with this test. However, during the sample collection, there might be a chance of tissue damage.
What is the turnaround time (TAT) for the custom IHC panel?
The custom IHC panel result is usually available within 5 working days after the sample collection. This duration may vary depending on the diagnostic clinic.
What are the various cancers that can be detected through the custom IHC panel?
A custom IHC panel can detect a wide range of cancers by targeting specific biomarkers indicative of different tumour types. This includes breast cancer, colorectal cancer, lung cancer, prostate cancer, adenocarcinoma, and others, aiding in accurate diagnosis and treatment selection.
How often should I undergo a custom IHC panel?
The frequency of undergoing custom IHC panel assessments depends on individual health status, sample availability, and the rate of biomarker alterations. It is advised to consult your healthcare provider to know the frequency.
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