Anti Sperm Antibody Test: Booking, Price, and Results
About Anti Sperm Antibody Test
| Field | Value |
|---|---|
| Also Known As | ASA Test, ASAB Test, Antisperm Antibodies Test, Sperm Antibody Test |
| Sample Type | Serum (blood) |
| Fasting Required | No fasting required |
| Report Time | 3 days |
| Recommended For | Men and women experiencing unexplained infertility |
| Price | Starting at ₹400 |
What is an Anti Sperm Antibody Test?
The Anti Sperm Antibody test is a blood test that checks for special immune proteins called antibodies that mistakenly target sperm. These proteins, if present in high levels, can interfere with a sperm's ability to reach and fertilise an egg. The test is also known as the ASA test, ASAB test, or Sperm Antibody Test. It is commonly ordered for couples who have been unable to conceive without a clear reason.
What Does an Anti Sperm Antibody Test Measure?
The test looks for specific immune proteins in the blood. The following components are evaluated during the test:
| Component | What It Checks |
|---|---|
| Antisperm Antibodies (ASA) | Proteins in blood or genital fluids that attack and damage sperm |
| IgG and IgA Immunoglobulins | IgG and IgM antibodies are found in the blood; IgA is found in the genital tract |
| Antibody Binding Location | Whether antibodies attach to the sperm head, tail, or midpiece, as binding to over 20 to 50% of sperm is clinically significant |
Why is an Anti Sperm Antibody Test Done?
Doctors order this test when other causes of infertility have been ruled out or when initial infertility results are unclear.
Common Symptoms That May Require This Test
The following symptoms may lead a doctor to recommend the Anti Sperm Antibody test:
- Difficulty conceiving despite regular unprotected intercourse
- Unexplained infertility with no other identifiable cause
- Sperm clumping together (known as agglutination) seen on a semen analysis
- Reduced sperm movement (motility) without a structural reason
- History of testicular injury, surgery, or prostate infection
Conditions This Test Can Help Detect
This test can help identify several conditions related to immune-related fertility problems:
- Immunologic infertility, where antibodies prevent sperm from fertilising an egg
- Antisperm antibodies as a specific cause of male infertility
- Immune responses triggered by testicular injury, vasectomy, biopsy, or genital infections
- Refractory (difficult-to-treat) infertility in both men and women
How to Prepare and What to Expect
Preparing for this test is straightforward. Here is what you need to know before your appointment.
Do You Need to Fast?
No fasting is required for the Anti Sperm Antibody test. You can eat and drink normally before providing a blood sample.
Practical Tips Before Your Test
A few simple steps will help ensure your sample is suitable for testing:
- Bring a detailed clinical history, including your symptoms, previous test results, and any prior surgeries or infections, as this is required for the test.
- Inform your doctor about all medications and supplements you are currently taking.
- Tell your doctor about any recent genital tract infections or testicular injuries.
- Wear comfortable clothing with easy access to your inner arm for blood collection.
- Men collecting a semen sample should follow the abstinence guidelines provided by the laboratory.
Step-by-Step Procedure
- Arrive at the collection centre or welcome the home collection phlebotomist at your scheduled time.
- Share your clinical history and any relevant documents with the healthcare provider.
- A small needle is inserted into a vein in your arm, and approximately 3 ml of blood is drawn into a sterile tube.
- The needle is removed, and a small cotton pad is pressed over the site. The whole process takes under five minutes.
- Your sample is labelled and stored at the correct temperature (2 to 8°C) before being sent to the laboratory.
- The sample is analysed using the EIA (enzyme immunoassay) method, and your report is ready within 3 days.
Factors That Can Affect Accuracy
Certain factors may influence the reliability of your test result:
- Very low sperm count (severe oligospermia) or absent sperm (azoospermia)
- High semen viscosity or debris in the sample
- Not following the recommended abstinence period before semen collection
- Recent infections or ongoing medication use
- Improper sample storage or delay in transport
Understanding Your Anti Sperm Antibody Test Results
Your results show the level of antisperm antibodies detected in your sample. A doctor should always review these findings alongside your full medical history.
| Parameter | Normal Range | Elevated / Positive |
|---|---|---|
| Antisperm Antibodies (Serum) | 0 to 60 U/mL | Above 60 U/mL |
| Direct Immunobead Test (Men) | Less than 20% sperm with bead attachment | 20% or more is considered positive |
| Direct Immunobead Test (Women) | Less than 10% | Above 10% is positive |
| MAR Test | Less than 10% sperm bound | Results at or above this threshold are considered significant |
These ranges are general guidelines. Your doctor will interpret your results based on your age, health history, and other factors. Always consult a qualified healthcare professional for personalised medical advice.
Results During Special Conditions
Some medical circumstances can affect how results are interpreted:
When the testicles are injured or a surgery such as a vasectomy is performed, the barrier that normally keeps sperm away from the immune system may be disrupted. Studies show that around 50% of men who have had a vasectomy develop antisperm antibodies as a result. Risk factors such as genital tract infections, undescended testes, and vasal obstruction can also raise antibody levels and should be discussed with your doctor when reviewing results.
How to Maintain Healthy Levels
These general wellness tips may help support reproductive health:
- Avoid testicular trauma where possible, and wear appropriate protective gear during contact sports.
- Seek prompt medical attention for any genital tract infections.
- If you are considering a vasectomy or other reproductive surgery, speak with your doctor about the potential effects on fertility.
Lupin Diagnostics Anti Sperm Antibody Test Price and Home Collection
The Anti Sperm Antibody test cost at Lupin Diagnostics starts at ₹400, and home sample collection is available for your convenience. The following table shows approximate prices across major Indian cities:
| City | Approximate Price (₹) |
|---|---|
| BHOPAL | 400 |
| CHENNAI | 400 |
| HYDERABAD | 400 |
| KOLKATA | 400 |
| NAVI MUMBAI | 400 |
| PUNE | 400 |
Prices are indicative and may vary by location. Please confirm the current price at the time of booking.
How to Book
- Select the test on the Lupin Diagnostics website.
- Choose your city and preferred time slot.
- Opt for home sample collection by a certified phlebotomist, or visit your nearest Lupin Diagnostics centre.
- Receive your report via email or WhatsApp within the stipulated turnaround time.
Home Collection
Lupin Diagnostics offers home sample collection for the Anti Sperm Antibody test across cities in India. All samples are processed in NABL-accredited laboratories staffed by trained professionals. Your digital report is delivered directly to you via email or WhatsApp, making it easy to share with your doctor.
Frequently Asked Questions
The Anti Sperm Antibody test is used to find out whether immune proteins are attacking sperm, which can reduce the chances of conception. It is typically ordered when other causes of infertility have been ruled out and is relevant for both men and women.
This test is recommended for couples who have been unable to conceive without a known cause. It may also be advised after a testicular injury, vasectomy, biopsy, or genital tract infection, as these can trigger an immune response against sperm.
Yes, both men and women can develop antisperm antibodies. In women, the immune system may treat sperm as a foreign substance and produce antibodies in response. These antibodies can then affect sperm motility and fertilisation.
The blood collection involves a brief sting when the needle is inserted. Most people find it easily tolerable. There may be mild bruising at the site afterwards, but this clears up quickly. There are no significant risks associated with the test.
Reports are typically available within 3 days of sample collection. At Lupin Diagnostics, your report is delivered digitally so you can share it with your doctor promptly.
Elevated antisperm antibodies do not automatically mean conception is impossible. Your doctor will review the levels in context and discuss your options. For some couples, assisted reproduction methods may be considered based on the overall fertility assessment.
Anti Sperm Antibody Test: Booking, Price, and Results
