Anti-MAG (Myelin Associated Glycoprotein) Antibody
Anti-MAG (Myelin Associated Glycoprotein) Antibody
The anti-MAG antibody test is used to identify the presence of anti-MAG (myelin-associated glycoprotein) antibodies in the blood sample.
MAG is a protein that is present in the myelin sheath, which acts as a protective covering for nerve fibers in the nervous system. The occurrence of antibodies targeting this particular protein is frequently linked to specific neurological disorders, particularly demyelinating peripheral neuropathies.
Thus, it is recommended to undergo this test to aid in the diagnosis and monitor the treatment of demyelinating peripheral neuropathies
Symptoms of peripheral neuropathy
Muscle weakness or cramps
Loss of muscle and bone
Changes in hair, skin, or nails
Loss of sensation or feeling in body parts
Loss of balance
Emotional disturbances
Sleep disruptions
Loss of bladder control
Dizziness
Irregular heartbeat
What is the Anti-MAG Antibody test used for?
The anti-MAG antibody test is used to :
Detect the presence of antibodies against myelin-associated glycoprotein
Diagnose certain neurological disorders, notably demyelinating peripheral neuropathies
Test preparation
No special preparation is required for the anti-MAG antibody test.
Interpretation of the Test Results
The units of measurement for the results are Bulhmann Titre Units (BTU)
|
Category |
Reference range
|
|
Negative |
<1000 BTU |
|
Low Positive |
1000-3000 BTU |
|
High Positive |
> 70000 BTU |
Positive test results
A positive test result indicates the presence of anti-MAG antibodies in the blood sample. High positive test result may indicate ongoing demyelination in peripheral neuropathies associated with MAG. Low positive test result may rule out MAG associated peripheral neuropathy but can be associated with other types of neuropathies.
Negative test results
A negative test result indicates the absence of anti-MAG antibodies in the blood sample.
FAQs
How is the sample collected for an anti-MAG antibody test?
A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes
What is the turnaround time (TAT) for anti-MAG antibody test?
The anti-MAG antibody test result is usually available within 2-6 working days after the sample collection. This duration may vary depending upon the diagnostic clinic
Are there any risks associated with anti-MAG antibody test?
This test involves negligible risk. There might be slight soreness or tenderness around the site where the blood is drawn. Rarely, the site can become infected
What is peripheral neuropathy?
Peripheral neuropathy includes a variety of disorders characterized by damage to the peripheral nerves, which are located outside the brain and spinal cord. As a result, individuals may experience symptoms like weakness, numbness, and pain, typically affecting the hands and feet
Do MAG antibodies occur in healthy individuals?
In healthy individuals, MAG antibodies are generally not detected. The presence of these antibodies usually indicates a pathological state, often seen in cases of demyelinating peripheral neuropathy
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