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Anti-Insulin Antibodies

Anti-Insulin Antibodies

The anti-insulin antibodies test is used to determine whether your body has generated antibodies against insulin or not.

Insulin, a hormone plays a crucial role in helping your body transfer blood sugar, also called glucose, from your bloodstream to your cells. Glucose is obtained from the foods and drinks you consume and serves as the main source of energy for your body. If blood glucose levels become too high, it can lead to serious health problems like diabetes.

Thus, it is recommended to get this test done to identify your risk of developing type 1 diabetes. 

This test is also known as Insulin Ab test, Insulin antibodies – serum, Diabetes - insulin antibodies, Insulin resistance - insulin antibodies

Symptoms of Type 1 diabetes

Feeling thirsty than usual

Feeling thirsty than usual

Urinating often

Urinating often

Weight loss

Weight loss

Feeling tired and weak

Feeling tired and weak

Having blurry vision

Having blurry vision

What is Anti-Insulin Antibodies test used for?

The anti-insulin antibodies test is performed:

To determine if you have or are at risk of developing type 1 diabetes

To determine if you have or are at risk of developing type 1 diabetes

To determine if you have an allergic reaction to insulin

To determine if you have an allergic reaction to insulin

When insulin can no longer control your diabetes

When insulin can no longer control your diabetes

When your blood sugar level fluctuates significantly while you are using insulin to manage your diabetes

When your blood sugar level fluctuates significantly while you are using insulin to manage your diabetes

Test preparation

No special preparation is required for an anti-insulin antibodies test.

Interpretation of the Test Results

The units of measurement for the results are Units per millilitre (U/mL) 

Reference range

Interpretation

> 18 U/ml

Positive

12 - 18 U/ml

Equivocal

< 12 U/ml

Negative

 

 

 

 

Deviation from normal levels indicates the following:

·       Presence of IgG and IgM antibodies against insulin may indicate an increased risk of developing type 1 diabetes.

Elevated levels of IgE antibody against insulin could potentially suggest an allergic reaction to the insulin

FAQs

How is the sample collected for an anti-insulin antibodies test?

A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes

What is the turnaround time (TAT) for anti-insulin antibodies test?

The anti-insulin antibodies test result is usually available within 2-6 working days after the sample collection. This duration may vary depending upon the diagnostic clinic

Are there any risks associated with anti-insulin antibodies test?

This test involves negligible risk. There might be slight soreness or tenderness around the site where the blood is drawn. Rarely, the site can become infected

Can autoantibody tests be used to diagnose diabetes?

No, type 1 diabetes and other types of diabetes are screened for, diagnosed, and monitored using blood glucose and/or A1c tests. Autoantibody tests, on the other hand, can be used after the diagnosis of diabetes to distinguish between type 1 and type 2 diabetes

Do anti-insulin antibodies occur in healthy individuals?

Normally, a healthy person will not have any antibodies against insulin circulating in their blood. However, individuals who use insulin to regulate their diabetes may have antibodies against insulin present in their blood

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