LupiKavach Fever Check 2

The LupiKavach Fever Check 2 includes a set of laboratory tests designed to identify the underlying cause of fever in patients. A fever is a frequently observed symptom that can suggest an underlying medical condition or infection. This package assists healthcare providers in diagnosing the condition or root cause of the fever, so they can provide the most effective treatment.

Signs and symptoms of common vitamin deficiencies, such as vitamin B12 deficiency, include:

The LupiKavach Fever Check 2 offers the following tests:

Complete Urine Examination: Detects abnormal substances in urine. The detection of these substances may indicate various disorders. The presence of bacteria, pus cells, blood cells, bilirubin, and epithelial cells in urine may indicate the occurrence of kidney disease or infection.

Complete Haemogram (CBC + ESR): Evaluates blood components (RBC, WBC, Hb, platelets, etc.) and inflammation (ESR) to assess overall health.

Serum Glutamic-Pyruvic Transaminase (SGPT)/Alanine transaminase (ALT): Measures the amount of ALT enzyme in the blood. Because ALT levels in the blood can rise when the liver is damaged, ALT blood test is used to assess liver health.

Peripheral Blood Smear for Malarial Parasite (PS for MP): Detects the presence of malarial parasite in the blood sample. Comprehensive information about the types of parasitemia, its density, and phases can be obtained through the examination of a peripheral blood smear.

C-Reactive Protein (CRP), Quantitative: Determines the amount of C-reactive protein (CRP) in the blood. The liver is responsible for the production of CRP in response to inflammation.

Dengue NS1 Antigen, Rapid: Used to detect the presence of non-structural (NS1) antigen in your blood. The NS1 antigen is a protein produced by the dengue virus in your blood. This test helps to diagnose the acute phase of primary and secondary dengue infections.

Typhidot, IgM: Detects IgM antibodies produced in response to Salmonella typhi infection in the body. Typhoid, commonly known as enteric fever, is caused by the bacterium Salmonella typhi. This test is performed to determine the cause of any persistent fever or the presence of signs and symptoms of typhoid fever.

Widal: Detects antibodies (agglutinins) in a blood sample against two Salmonella enterica antigens (O & H). Used to identify typhoid and paratyphoid fever. 

Dengue IgG & IgM Rapid antibodies: Detects the presence of IgG and IgM antibodies. This is an immunochromatographic test used for the qualitative identification and differentiation of specific IgM and IgG antibodies against the dengue virus. 

Complete Urine Examination

• Urine usually contains a variety of chemicals and substances. It is generally clear with a light yellow colour. The pH level should be between 4.5 and 8, indicating its acidity or alkalinity.
• Urine is typically free of glucose, protein, and ketones. Under a microscope, a normal examination will reveal up to 5 red blood cells, 5 white blood cells, and no bacteria. Any results that deviate from these may indicate a specific health issue.

Complete Haemogram (CBC + ESR)

• Abnormal levels of hemoglobin, hematocrit, or RBCs can be signs of anemia, heart disease, or iron deficiency.
• Low white blood cell count may be due to a bone marrow disorder, autoimmune disorder, or cancer.
• High white blood cell count may be due to infection, inflammation, or a reaction to a medication.
• High ESR may be an indication of the conditions that cause inflammation such as arthritis, kidney diseases, inflammatory bowel disease, infections, heart diseases, and certain cancers.
• Low ESR may be an indication of blood disorders such as polycythemia, sickle cell disease, leucocytosis, and certain kidney and liver problems.

Serum Glutamic-Pyruvic Transaminase (SGPT)/Alanine transaminase (ALT)

• Very high level of ALT (> 10 times the normal level) is usually caused by acute hepatitis as a result of viral infection.
• High level of ALT (4 times the normal level) is usually caused by chronic hepatitis, biliary obstruction, or cirrhosis.
• In most liver diseases, ALT is higher than AST and the AST/ALT ratio is low (<1). AST/ALT ratio greater than 1 is usually caused by alcoholic hepatitis, cirrhosis, heart or muscle injury.

Peripheral Blood Smear for Malarial Parasite (PS for MP)

C-Reactive Protein (CRP), Quantitative

A CRP test result ranging from 10 to 100 mg/dL is considered moderately elevated. This result could point to any of the following conditions:

• Systemic inflammation caused by rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), or other autoimmune diseases
• Heart attack (myocardial infarction)
• Pancreatitis
• Bronchitis

A CRP test result of more than 100 mg/dL is considered a significant elevation. This result could point to any of the following conditions:

• Bacterial infections
• Infections caused by viruses
• Vasculitis throughout the body
• Serious injury (trauma)

Higher levels of CRP may indicate systemic inflammation, which may be linked to pre-diabetes, diabetes, insulin resistance, a long-term infection, and conditions associated with an increased risk of cardiovascular disease.

Dengue NS1 Antigen, Rapid

Note: It is advised to perform an NS1 Antigen Rapid test within the first five days of a fever. Dengue fever antibodies IgG & IgM by ELISA are the suggested test after 7-10 days of ongoing fever.

Typhidot IgM

Widal

Positive test result

• If the patient's serum contains an anti-Salmonella antibody, the reagent's corresponding antigen will be activated and cause visible agglutination (clumping) at the bottom of the test tube after 18 hours.
• The antibody titre is the highest dilution of the patient's serum sample that causes an observable agglutination with the Widal test antigen suspensions.
• Active infection is indicated by serum samples with titres of 1:80 or higher for O agglutination and 1:160 or higher for H agglutination.
• The diagnosis of enteric fever is confirmed by a rise in titres (fourfold or more) in the two blood samples collected ten days apart.

Negative test result

A negative test result shows that there was no agglutination (clumping) at the bottom of the test tube, meaning that there are no clinically significant levels of the corresponding antibody in the patient's serum.