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PAP Smear, Conventional Test

PAP Smear, Conventional Test

The Papanicolaou (PAP) Smear, Conventional Test is a screening test for cervical cancer that detects abnormal cells in the cervix, which may indicate precancerous changes, infection, or other cervical conditions. Cervical cancer is one of the most preventable cancers, and early detection through regular screening significantly reduces the risk of progression.

This test is commonly recommended for women aged 21 and older and is a crucial part of routine gynecological care. Human papillomavirus (HPV) infection is the primary cause of cervical cancer, and a PAP smear helps identify abnormal cellular changes before they become cancerous.

What is the PAP Smear, Conventional Test Used For?

This test is used to:

  • Screen for cervical cancer and precancerous changes.
  • Detect abnormal cells in the cervix (dysplasia or atypical cells).
  • Identify infections, inflammation, and HPV-related changes.
  • Monitor patients with a history of abnormal PAP results.

Symptoms of Cervical Cancer

Early-stage cervical cancer often has no symptoms, making regular Pap smears and HPV testing essential. As the disease progresses, symptoms may include

Unusual vaginal bleeding- Bleeding between periods, Postmenopausal bleeding, Bleeding after intercourse, douching, or pelvic exams

Unusual vaginal bleeding- Bleeding between periods, Postmenopausal bleeding, Bleeding after intercourse, douching, or pelvic exams

Abnormal vaginal discharge- Watery, bloody, or foul-smelling discharge, Heavy or persistent discharge

Abnormal vaginal discharge- Watery, bloody, or foul-smelling discharge, Heavy or persistent discharge

Pelvic pain or discomfort- Pain during intercourse, Chronic pelvic or lower back pain

Pelvic pain or discomfort- Pain during intercourse, Chronic pelvic or lower back pain

Leg swelling (lymphatic obstruction)

Leg swelling (lymphatic obstruction)

Difficulty urinating or blood in urine

Difficulty urinating or blood in urine

Unexplained weight loss or fatigue

Unexplained weight loss or fatigue

Preparation for the Test

The sample is collected by gently scraping the cervix using a spatula and cytobrush, then spread onto a glass slide for microscopic examination. Avoid vaginal intercourse, douching, or using tampons 24-48 hours before the test. Do not schedule the test during menstruation, as blood may interfere with the results. Inform your doctor about any history of abnormal PAP tests or HPV infections.

Interpretation of Results

  • Normal (Negative for intraepithelial lesion or malignancy)- No abnormal cells detected.
  • Atypical Squamous Cells of Undetermined Significance (ASC-US) or Low-Grade Squamous Intraepithelial Lesion (LSIL)- Mild abnormality, often caused by HPV; may require follow-up testing.
  • High-Grade Squamous Intraepithelial Lesion (HSIL) or Atypical Glandular Cells (AGC)- Requires further testing, such as colposcopy or biopsy, to rule out precancer or cancer.
  • Positive for malignancy- Suggests cervical cancer; further evaluation is necessary.

FAQs

How often should I get a PAP smear?

    • Every 3 years for women aged 21-29.
    • Every 3-5 years for women aged 30-65, depending on HPV co-testing.

Does a PAP smear test for HPV?

No, but an HPV test may be done alongside a PAP smear for high-risk HPV strains.

Can I still get cervical cancer if my PAP smear is normal?

While unlikely, it’s possible; regular screenings are important for early detection.

Is a PAP smear painful?

It may cause mild discomfort, but it is generally not painful and lasts only a few minutes.

What happens if my PAP smear is abnormal?

Your doctor may recommend repeat testing, HPV testing, or a colposcopy with biopsy.

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