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Mumps IgM Antibody Test

Mumps IgM Antibody Test

The Mumps IgM Antibody Test is a laboratory test used to detect IgM antibodies against the mumps virus. Mumps is a highly contagious viral infection that primarily affects the salivary glands, leading to painful swelling. The test helps identify recent or active mumps infection, as IgM antibodies are the first to appear following exposure to the virus.

Mumps is caused by the mumps virus, a member of the Paramyxoviridae family, and spreads through respiratory droplets, direct contact, or contaminated surfaces. Symptoms typically appear 16–18 days after exposure. While the disease is usually mild, complications such as meningitis, encephalitis, orchitis (testicular inflammation in males), oophoritis (ovarian inflammation in females), and pancreatitis can occur.

Vaccination with the Measles, Mumps, and Rubella (MMR) vaccine is the most effective preventive measure. However, mumps outbreaks still occur, particularly in crowded environments such as schools and colleges.

What is the Mumps IgM Antibody Test Used For?

This test is used to:

  • Diagnose an active or recent mumps infection.
  • Differentiate mumps from other causes of salivary gland swelling.
  • Support outbreak investigations and public health monitoring.
  • Determine infection in unvaccinated or partially vaccinated individuals.

Symptoms of Mumps

Mumps symptoms typically appear 16-18 days after exposure and may include

Swollen, painful salivary glands (parotitis)

Swollen, painful salivary glands (parotitis)

Fever

Fever

Headache

Headache

Muscle aches

Muscle aches

Fatigue and weakness

Fatigue and weakness

Loss of appetite

Loss of appetite

Pain while chewing or swallowing

Pain while chewing or swallowing

Preparation for the Test

No special preparation is needed. A blood sample is collected from a vein. Inform the doctor of any recent vaccinations or infections, as they may affect results.

Interpretation of Results

  • Positive IgM: Suggests an active or recent mumps infection.
  • Negative IgM: No evidence of recent infection, but further testing (IgG or PCR) may be needed.
  • Equivocal Result: A borderline result may require a repeat test or additional testing.

FAQs

How long do IgM antibodies remain detectable?

IgM antibodies typically appear within 5 days of infection and remain detectable for several weeks.

Can this test confirm immunity to mumps?

No, an IgG antibody test is required to determine long-term immunity.

Who should get tested?

  • Individuals with symptoms of mumps
  • Unvaccinated or partially vaccinated individuals
  • People exposed to confirmed mumps cases

Healthcare workers in outbreak settings

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