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Fructosamine

Fructosamine

The fructosamine test measures the level of glucose bound to proteins in the serum or plasma. Fructosamine is formed when glucose combines with proteins.

 

Glucose, a sugar used by the human body as the primary energy source for its cells, is acquired from the food consumed. With an elevated concentration of glucose in the bloodstream, a greater proportion of it will bind to proteins. As proteins remain present in the blood for approximately 14 to 21 days, the fructosamine test provides an overview of the average glucose levels over the previous 2 to 3 weeks. 

Thus, it is recommended to undergo this test to understand how well glucose levels have been managed in diabetic individuals in recent weeks

Symptoms of diabetes

Feeling thirsty very often

Feeling thirsty very often

Feeling hungry often

Feeling hungry often

Fatigue

Fatigue

Urinating a lot

Urinating a lot

Losing weight without any effort

Losing weight without any effort

Numbing or tingling of hands and feet

Numbing or tingling of hands and feet

Slow healing of any cuts or wounds

Slow healing of any cuts or wounds

Recurrent infections

Recurrent infections

Dry skin

Dry skin

Blurred vision

Blurred vision

Who should get tested?

If you have diabetes and are experiencing one or more of the following conditions, your healthcare provider may request the fructosamine test for you.

Hemoglobinopathy, an abnormal form of hemoglobin

Hemoglobinopathy, an abnormal form of hemoglobin

Anemia

Anemia

Recent loss of blood

Recent loss of blood

Other conditions such as hemochromatosis that can impact the count or lifespan of red blood cells (RBCs)

Other conditions such as hemochromatosis that can impact the count or lifespan of red blood cells (RBCs)

Test preparation

This test requires no special preparation.

Interpretation of the Test Results

Reference range for the fructosamine, serum is 200-285 micromoles per liter (mcmol/L).

Fructosamine generally serves as an indicator of glycemic control in diabetic individuals within the past 1 to 3 weeks. Elevated levels are indicative of inadequate control

FAQs

How is the sample collected for the fructosamine test?

A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes

Does this test pose any risks?

This test carries negligible risks. However, you may experience bleeding, infection, bruising, and a feeling of light-headedness

What is the turnaround time (TAT) for fructosamine test result?

The test results can be obtained within 1-2 working days after the sample collection. TAT may vary, depending on the particular diagnostic clinic

What factors can affect the fructosamine test result?

Elevated levels of vitamin C (ascorbic acid), lipaemia (turbidity in the samples due to lipoprotein particles), and haemolysis (destruction of red blood cells) can affect the accuracy of test results

What is the difference between fructosamine test and hemoglobin A1c test?

The fructosamine test is used to determine the average blood glucose level over a period of two to three weeks, whereas the hemoglobin A1c test assesses the average glucose level over the past two to three months. Furthermore, these tests analyze different proteins that glucose binds with: the hemoglobin A1c test measures hemoglobin, while the fructosamine test measures total proteins

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