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Fibrinogen

Fibrinogen

The fibrinogen test determines the level of fibrinogen in your blood. Fibrinogen is a liver protein that helps in the clotting of blood in case of vascular or tissue injury. It plays a major role in both bleeding and clotting. A deficiency of fibrinogen indicates abnormal bleeding in the body.

Abnormal levels of fibrinogen may indicate various conditions, like afibrinogenemia (absence of fibrinogen), hypofibrinogenemia (reduced levels of fibrinogen), and hyperfibrinogenaemia (increased fibrinogen levels).  Thus, getting a fibrinogen test is recommended if you have any signs of excessive bleeding to detect the amount of fibrinogen activity in your blood and to prevent bleeding-related complications.

Fibrinogen test is also known as Fibrinogen Activity, Fibrinogen Antigen Test, Hypofibrinogenemia Test, Cardiac Fibrinogen, Serum Fibrinogen Test, Plasma Fibrinogen, and Factor 1 Assay

What is the fibrinogen test used for?

Fibrinogen test is used in the diagnosis of:

Bleeding disorders of the gastrointestinal tract

Bleeding disorders of the gastrointestinal tract

Chronic liver diseases

Chronic liver diseases

Congenital bleeding disorders

Congenital bleeding disorders

Disseminated intravascular coagulation or DIC

Disseminated intravascular coagulation or DIC

Heart bypass surgery

Heart bypass surgery

Recurrent miscarriages

Recurrent miscarriages

Symptoms of low fibrinogen:

A few common symptoms of low fibrinogen include:

Bleeding gums

Bleeding gums

Gastrointestinal tract bleeding

Gastrointestinal tract bleeding

Blood in your urine or stool

Blood in your urine or stool

Coughing out blood

Coughing out blood

Frequent nosebleeds

Frequent nosebleeds

Ruptured spleen

Ruptured spleen

Excessive bruising

Excessive bruising

Test preparation

No special preparation is required before the fibrinogen test. Ensure your healthcare provider is aware if you are taking any blood thinner medications before the test

Interpretation of the Test Results

The normal range of fibrinogen is given as grams per litre or milligrams per decilitre.

Parameters

Normal Reference Range

Fibrinogen

2.0 to 4.0 g/L or 200 to 400 mg/dL

 

Deviation from normal levels indicates the following:

Higher or lower than normal fibrinogen levels may indicate the following conditions:

·       Fibrinogen deficiency

·       Bleeding disorders such as haemophilia and disseminated intravascular coagulation (DIC)

·       Fibrinolysis (breakdown of fibrin)

Haemorrhage (excess bleeding)

FAQs

How is the fibrinogen test performed?

During this blood test, a healthcare professional will take a small amount of blood from a vein in your arm using a small needle, which is collected in a test tube or vial. This procedure takes no longer than five minutes

What are the risks involved in a fibrinogen test?

This test involves negligible risk. During a blood test, one may experience minor pain or bruising where the needle was inserted, but most symptoms will subside quickly

How long should I wait for my fibrinogen test results?

Test results will be available within a week. You may receive your test results via email or regular mail or you can receive a call from the doctor's office to go over the results of the fibrinogen test or to schedule a follow-up appointment

What factors might affect my fibrinogen test results?

Acute blood loss, stress, severe trauma, burns, aging, obesity, using oral contraceptive pills, insulin resistance, tobacco usage, and pregnancy can affect your test results. So, it is recommended to consult your healthcare provider before fibrinogen testing

Should I provide information about my fibrinogen deficiency to my other healthcare providers?

Yes, you have to provide information about your test results when you consult other healthcare providers because the deficiency of fibrinogen affects the body’s ability to clot effectively during and after any surgical procedures

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