Faecal Elastase
Faecal Elastase
A fecal elastase test is used to measure the amount of elastase in the stool sample.
Elastase is a digestive enzyme produced by exocrine tissue in the pancreas that helps digest food. This test measures the elastase in the feces and evaluates the functioning of the pancreas. Elastase breaks down carbohydrates, fats, and proteins in the body for cell development, repair, and energy production. When there is a lack of elastase present in stool, it could suggest an inadequate production and/or release of elastase and other digestive fluids by the pancreas. This condition is referred to as exocrine pancreatic insufficiency (EPI).
Thus, it is recommended to undergo this test to diagnose various conditions that affect the pancreas, such as EPI, pancreatitis, cystic fibrosis in children, and pancreatic cancer
Symptoms of pancreatic disease
Abdominal cramps
Greasy stools
Nausea and vomiting
Vitamin deficiencies
Weight loss
What is the fecal elastase test used for?
Fecal elastase can be performed for many reasons including
To monitor the functioning of the pancreas
To diagnose exocrine pancreatic insufficency
To indicate conditions like pancreatitis that damage the pancreas
To monitor exocrine pancreatic function in diabeties,cystic fibrosis and chronic pacreatitis patients
Preparation for Test
Fasting is not required for the fecal elastase test. Stool samples must be collected in a clean container and avoid any contamination with water or urine
Interpretation of Test Results
The results are given in micrograms/gram (ug/g). Typically, the standard results are:
· Normal exocrine pancreatic sufficiency >200 (ug/g)
· Moderate to mild exocrine pancreatic sufficiency 100-200 (ug/g)
· Severe exocrine pancreatic sufficiency <100 (ug/g)
Deviation from normal levels indicates the following:
An insufficient level of elastase could indicate the presence of EPI. Abnormal test results may be described as either "moderate" or "severe pancreatic insufficiency."
FAQs
What causes pancreatic insufficiency?
It is mainly caused by chronic pancreatitis. Other causes include celiac disease, autoimmune pancreatitis, and Crohn's disease. In children, pancreatic insufficiency is caused by cystic fibrosis
What are the risk factors of the fecal elastase test?
There are no risk factors associated with the fecal elastase test
How frequently should the fecal elastase test be carried out?
A fecal elastase test is usually done between 6 and 12 months, and it may be more frequent in cases of exocrine pancreatic insufficiency (EPI).
What is the significance of elastase in feces?
Elastase serves as an indicator of pancreatic function. It helps to break down carbohydrates and use them for energy and growth in the body
Can medications affect the fecal elastase test?
The test results can be affected by certain medications, including pancreatic enzyme supplements. Hence, it is advisable to disclose all medications or supplements you are currently taking to your doctor before undergoing the test
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