Endomysial Antibody IgG
Endomysial Antibody IgG
The endomysial antibody IgG test is used to detect IgG antibodies that are produced in response to celiac disease. This test is conducted when an individual is deficient in IgA antibodies.
Individuals with celiac disease experience an abnormal immune response to gluten, a protein found in wheat, barley, and rye products. The body produces endomysial antibodies (EMA) in response to gluten, causing inflammation in the intestine. This inflammation can hinder the absorption of nutrients from food, leading to malnutrition and other complications due to chronic damage to the small intestine. Thus, getting this test done is recommended to aid in the diagnosis of celiac disease.
Symptoms of celiac disease
Repeated stomach pain and bloating
Weight loss
Chronic diarrhea or constipation
Increased internal gas
Fatty and foul smelling stool
Muscle or joint aches
Itchy rashes
Anemia
Depression
Mouth sores
What is the Endomysial Antibody IgG test used for?
The endomysial antibody IgG test is recommended
To diagnose celiac disease when symptoms of the disease are present
Preparation for the test
No specific preparations are needed for the endomysial antibody IgG test. It is important to maintain a normal diet that includes gluten before the test, as switching to a gluten-free diet could lead to false-negative results.
Interpretation of test results
The results of endomysial antibody IgG test are available as either positive or negative.
Positive test results
A positive test result indicates that IgG endomysial antibodies were found in the blood sample, suggesting the presence of celiac disease.
Negative test results
A negative test result indicates that no IgG endomysial antibodies were found in the blood sample.
FAQs
How is the sample collected for the endomysial antibody IgG test?
A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes.
Are there any risks associated with the endomysial antibody IgG test?
No, there are no associated risks with the endomysial antibody IgG test. It is a simple blood test that carries minimal risks, such as experiencing a slight sting or bruise at the needle insertion site. Typically, these discomforts subside within a short period of time, ranging from a few minutes to a couple of hours. In rare cases, there is a possibility of infection at the needle insertion site.
What is the turnaround time (TAT) for the results of the endomysial antibody IgG test?
The endomysial antibody IgG test result is usually available within 9 days after sample collection. This duration may vary depending on the diagnostic clinic.
Could elevated EMA levels be indicative of other health issues?
Elevated levels of EMA are typically associated with celiac disease, but they can also be found conditions like dermatitis herpetiformis, which is a skin manifestation of celiac disease.
What steps should someone take if they have a positive test result?
In case of a positive result on the endomysial antibody IgG test, it is advisable to seek advice from a gastroenterologist (specializes in digestive system conditions). Additionally, it is recommended to consult a dietitian for assistance with dietary modifications.
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