Endomysial Antibody, IgA
Endomysial Antibody, IgA
The endomysial antibody IgA test is used to detect IgA antibodies that are produced in response to celiac disease.
Individuals diagnosed with celiac disease exhibit an abnormal immune reaction towards gluten, a protein present in wheat, barley, and rye. In response to gluten, the body generates endomysial antibodies (EMA), which result in inflammation in the intestine. This inflammation can impede the absorption of essential nutrients from food, ultimately leading to malnutrition and various complications arising from long-term damage to the small intestine. Therefore, getting this test done is recommended to aid in the diagnosis of celiac disease.
Symptoms of celiac disease
Repeated stomach pain and bloating
Weight loss
Chronic diarrhea or constipation
Increased internal gas
Fatty and foul smelling stool
Muscle or joint aches
Itchy rashes
Anemia
Depression
Mouth sores
What is the Endomysial Antibody, IgA test used for?
The endomysial antibody, IgA test is recommended
To diagnose celiac disease when symptoms of the disease are present
To monitor the adherence of a gluten-free diet in patients diagnosed with celiac disease
Preparation for the test
No specific preparations are needed for the endomysial antibody, IgA test. It is important to maintain a normal diet that includes gluten before the test, as switching to a gluten-free diet could lead to false-negative results.
Interpretation of test results
The results of endomysial antibody, IgA test are available as either positive or negative.
Positive test results
A positive test result indicates that IgA endomysial antibodies were found in the blood sample, suggesting the presence of celiac disease.
Negative test results
A negative test result indicates that no IgA endomysial antibodies were found in the blood sample.
FAQs
How is the sample collected for the endomysial antibody IgA test?
A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes.
Are there any risks associated with the endomysial antibody IgA test?
No, there are no associated risks with the endomysial antibody IgA test. It is a simple blood test that carries minimal risks, such as experiencing a slight sting or bruise at the needle insertion site. Typically, these discomforts subside within a short period of time, ranging from a few minutes to a couple of hours. In rare cases, there is a possibility of infection at the needle insertion site.
What is the turnaround time (TAT) for the results of the endomysial antibody IgA test?
The endomysial antibody IgA test result is usually available within 9 days after sample collection. This duration may vary depending on the diagnostic clinic.
Can the endomysial antibody IgA test indicate the severity of celiac disease?
The endomysial antibody IgA test does not assess the extent of celiac disease directly; instead, it reflects the immune system's reaction to gluten. Its main purpose is to aid in the diagnosis of celiac disease and monitoring of dietary compliance in individuals with celiac disease.
Can healthy individuals have abnormal EMA levels?
High levels of EMA are not commonly seen in healthy individuals. These antibodies are typically detected in individuals with celiac disease or related disorders.
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