Catecholamines 24-Hour Urine Test | Adrenal Tumor Diagnosis
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Catecholamines, 24 hours Urine

Catecholamines, 24 hours Urine

Catecholamines, 24 hours Urine test is used to measure the levels of catecholamines or catecholamine metabolites (break-down products) in the urine sample over 24 hours.

The adrenal glands produce catecholamines, which are hormones that are released during times of physical or emotional stress. This group of hormones includes epinephrine (also referred to as adrenalin), norepinephrine, and dopamine. They can transmit nerve impulses within the brain, constrict blood vessels, and elevate the heart rate.

Getting this test done is recommended for aiding the diagnosis of rare adrenal tumours such as neuroblastoma, pheochromocytoma etc.

This test is also known as:

Dopamine - urine test, Adrenalin - urine test, Epinephrine - urine test, Urine metanephrine, Normetanephrine, Norepinephrine - urine test, Urine catecholamines

Symptoms Of Rare Adrenal Tumours

Headaches

Headaches

Sweating

Sweating

Rapid heart rate (palpitations)

Rapid heart rate (palpitations)

Trouble breathing

Trouble breathing

Panic attack

Panic attack

High blood pressure

High blood pressure

Stomach pain

Stomach pain

Weight loss

Weight loss

Pale skin

Pale skin

Constipation

Constipation

Blurry vision

Blurry vision

Increased thirst

Increased thirst

Frequent urination

Frequent urination

What Is a Catecholamines, 24 Hours Urine Test Used For?

This test may be useful:

As a follow-up test to urine metanephrine or plasma free metanephrines for confirming the diagnosis of adrenal gland tumours

As a follow-up test to urine metanephrine or plasma free metanephrines for confirming the diagnosis of adrenal gland tumours

To monitor those who are receiving treatment for adrenal gland tumours

To monitor those who are receiving treatment for adrenal gland tumours

Test preparation

Refrain from consuming tea, coffee, bananas, citrus fruits, vanilla, walnuts, fava beans, avocados, cocoa, licorice, vanilla, and chocolate for a period of 2 to 3 days prior to the test, as these items can impact the accuracy of the test results. It is advisable to drink plenty of non-caffeinated drinks and avoid tobacco consumption throughout the 24-hour urine collection period. Ensure your doctor is aware of what prescription drugs, over-the-counter medicines, or dietary supplements you are taking. Ask your doctor for details about pre-test preparations, and make sure to follow instructions closely

Interpretation of the Test Results

The units of measurement for the results are Micrograms per 24 hours (mcg/24 hours)

Condition

Hormone levels in 24-hour urine sample

Epinephrine

0.5 to 20 mcg/24-hours

Norepinephrine

15 to 80 mcg/24-hours

Dopamine

65 to 400 mcg/24-hours

Metanephrine

24 to 96 mcg/24-hours

Normetanephrine

75 to 375 mcg/24-hours

Total urine catecholamines

14 to 110 mcg/24-hours

 

 

 

 

 

 

 

 

 

Elevated levels of urinary catecholamines may be caused due to:

·       Acute anxiety

·       Severe stress

·       Neuroblastoma (rare)

·       Pheochromocytoma (rare)

·       Ganglioblastoma (very rare)

Ganglioneuroma (very rare)

FAQs

How is the sample collected for a Catecholamines, 24 hours Urine test?

In order to provide a urine sample for this test, you will need to collect all of your urine over a 24-hour period. Begin by emptying your bladder fully in the morning without collecting it. Remember to take note of the time. From then on, collect your urine each time you use the bathroom throughout the day. To complete the 24-hour collection, urinate into the container on the morning of the next day and make sure to note the precise time

What are the risks involved in a Catecholamines, 24 hours Urine test sample collection?

Urine sample collection for Catecholamines, 24 hours Urine test does not pose any risks

Can medications interfere with the accuracy of the test results?

Yes, medications such as certain antihypertensives and antidepressants can have an impact on catecholamine levels. To ensure accurate results, it is important to disclose all medications taken to the healthcare provider before the test

How is pheochromocytoma treated if detected?

If pheochromocytoma is detected, the treatment approach will depend on various factors. These may include the size and location of the tumour, as well as the presence of any symptoms or complications. Treatment options for pheochromocytoma typically involve surgical removal of the tumour. In some cases, medication may be prescribed to manage symptoms or to prepare the patient for surgery. Regular monitoring and follow-up care are essential to ensure the effectiveness of the treatment and to prevent any potential recurrence

How is the collected urine stored during the 24-hour collection period?

Proper storage of the urine sample is crucial to prevent degradation of albumin and ensure accurate test results. Keep the collected urine in a cool and dark place such as a refrigerator until it is handed over to the laboratory

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