Cardiac Injury Profile (Maxi) Test
The cardiac injury profile (maxi) test is a comprehensive panel test used to ascertain acute cardiac injury or the extent of damage to the heart muscle following a heart attack. This test comprises of the following 4 tests:
- Creatine Phosphokinase MB (CPK-MB)
- Myoglobin, Serum
- NT-pro BNP
- Troponin-I, High Sensitive (hsTnl)
The cardiac injury profile (maxi) test may be ordered by a healthcare provider to find out the extent of injury to the heart muscle in case of a heart attack.
Symptoms of heart attack
Chest discomfort or pain
Upper body pain
Stomach pain
Shortness of breath
Anxiety
Light headedness
Sweating
Nausea and vomiting
Heart palpitations
Which tests are included under Cardiac Injury Profile (Maxi)?
The cardiac injury profile (maxi) test is used to evaluate:
Creatine Phosphokinase MB (CPK-MB):
-
CPK is an enzyme (protein) present in various body tissues such as the heart, skeletal muscle, and brain. Higher than normal levels of CPK in your blood may be a sign of muscle injury, heart disease, and brain stroke. CPK is an isoenzyme (different forms of the same enzyme), which is found in the heart as CPK-MB. The Creatine phosphokinase (CPK)-MB test measures the level of CPK in the blood sample.
Myoglobin, Serum:
-
Your heart and skeletal muscles contain a protein called myoglobin. Myoglobin is released into the blood when you suffer a heart attack or significant muscle damage. Myoglobin test is used to measure the amount of myoglobin protein in a given blood sample. This test is done to aid in the diagnosis of conditions such as muscular dystrophy that cause progressive muscle damage.
NT-pro BNP:
-
N-terminal pro b-type natriuretic peptide, or NT-pro-BNP, is a type of natriuretic peptide synthesized by the heart. It is generally found only in small amounts in the bloodstream. If the level rises, it is an indication that the heart is not pumping enough blood to the body as required. NT-pro-BNP test measures the level of NT-pro-BNP in the blood. It is useful in diagnosing heart failure in an individual.
Troponin-I, High Sensitive (hsTnl)
-
Troponin-I test is a highly sensitive blood test that measures the level of troponin-I in your blood. Troponin-I is a protein particular to the heart muscle. Normally, troponin-I levels in the blood are undetectable. Troponin-I is released into the bloodstream when the heart muscle is injured or damaged.
Who should get tested?
People who have high risk of heart disease should get tested, they include people:
Who have advanced age
Who have family history of heart disease
Who are overweight
Who smoke cigarettes
Who have high blood pressure
Consume unhealthy diet
Who are sedentary
Who have diabetes
Who have pre-existing heart disease
Preparation for the test
The cardiac injury profile (maxi) test does not require any special preparations.
Interpretation of test results
|
Test name |
Reference Range |
Inference |
|
Creatine Phosphokinase MB (CPK-MB)
|
Male: 55-170 units/L Female: 30-135 units/L (Normal reference range of serum CPK-MB is 3 to 5% of total CPK i.e. 5 to 25 IU/L) |
Higher than normal levels indicate damage to the heart muscles |
|
Myoglobin, Serum
|
25 to 72 ng/mL |
High level: May be caused due to heart attack Low level: May be caused due to conditions such as rheumatoid arthritis |
|
NT-pro BNP
|
100-300pg/ml |
High levels indicate that the person suffers from heart failure |
|
Troponin-I, High Sensitive (hsTnl)
|
· 0.5 mcg/L
· 0.6-2.3 mcg/L
· >2.3 mcg/L |
Normal
Weakly positive or suggestive of myocardial injury Highly positive or suggestive of acute myocardial infarction |
FAQs
How is the sample collected for the cardiac injury profile (maxi) test?
During this blood test, a healthcare professional will take a small amount of blood from a vein in your arm, using a needle, which is then collected in a test tube or vial. This process is usually completed within a few minutes.
Are there any risks associated with the cardiac injury profile (maxi) test?
There are no known risks. During a blood test, one may experience minor pain or bruising where the needle was inserted, but most symptoms will subside quickly.
What are the benefits of undergoing the cardiac injury profile (maxi) test?
This test yields important information about your heart health in a hassle-free manner, as it is a simple blood test. This test enables your healthcare provider to chart out an appropriate treatment plan for managing acute cardiac injury.
What is the turnaround time (TAT) for the cardiac injury profile (maxi) test?
The test results are made available within 24 hours of sample collection as this test yields critical information about a person’s heart health. Moreover, A rapid diagnosis is essential to save a person's life in the event of a heart attack.
What further tests might I require if I have an abnormal cardiac injury profile (maxi) test result?
If your levels of the cardiac injury profile (maxi) test are elevated, it may be necessary to conduct further tests to confirm the diagnosis and determine the appropriate treatment. Additional tests may involve imaging of your heart and an electrocardiogram (ECG).