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Cardiac Injury Profile (Maxi) Test

The cardiac injury profile (maxi) test is a comprehensive panel test used to ascertain acute cardiac injury or the extent of damage to the heart muscle following a heart attack. This test comprises of the following 4 tests:

  • Creatine Phosphokinase MB (CPK-MB)
  • Myoglobin, Serum
  • NT-pro BNP
  • Troponin-I, High Sensitive (hsTnl)


The cardiac injury profile (maxi) test may be ordered by a healthcare provider to find out the extent of injury to the heart muscle in case of a heart attack.

Symptoms of heart attack

Chest discomfort or pain

Chest discomfort or pain

Upper body pain

Upper body pain

Stomach pain

Stomach pain

Shortness of breath

Shortness of breath

Anxiety

Anxiety

Light headedness

Light headedness

Sweating

Sweating

Nausea and vomiting

Nausea and vomiting

Heart palpitations

Heart palpitations

Which tests are included under Cardiac Injury Profile (Maxi)?

The cardiac injury profile (maxi) test is used to evaluate:

Creatine Phosphokinase MB (CPK-MB):

  • CPK is an enzyme (protein) present in various body tissues such as the heart, skeletal muscle, and brain. Higher than normal levels of CPK in your blood may be a sign of muscle injury, heart disease, and brain stroke. CPK is an isoenzyme (different forms of the same enzyme), which is found in the heart as CPK-MB. The Creatine phosphokinase (CPK)-MB test measures the level of CPK in the blood sample.

Myoglobin, Serum:

  • Your heart and skeletal muscles contain a protein called myoglobin. Myoglobin is released into the blood when you suffer a heart attack or significant muscle damage. Myoglobin test is used to measure the amount of myoglobin protein in a given blood sample. This test is done to aid in the diagnosis of conditions such as muscular dystrophy that cause progressive muscle damage.

NT-pro BNP:

  • N-terminal pro b-type natriuretic peptide, or NT-pro-BNP, is a type of natriuretic peptide synthesized by the heart. It is generally found only in small amounts in the bloodstream. If the level rises, it is an indication that the heart is not pumping enough blood to the body as required. NT-pro-BNP test measures the level of NT-pro-BNP in the blood. It is useful in diagnosing heart failure in an individual.

Troponin-I, High Sensitive (hsTnl)

  • Troponin-I test is a highly sensitive blood test that measures the level of troponin-I in your blood. Troponin-I is a protein particular to the heart muscle. Normally, troponin-I levels in the blood are undetectable. Troponin-I is released into the bloodstream when the heart muscle is injured or damaged.

Who should get tested?

People who have high risk of heart disease should get tested, they include people:

Who have advanced age

Who have advanced age

Who have family history of heart disease

Who have family history of heart disease

Who are overweight

Who are overweight

Who smoke cigarettes

Who smoke cigarettes

Who have high blood pressure

Who have high blood pressure

Consume unhealthy diet

Consume unhealthy diet

Who are sedentary

Who are sedentary

Who have diabetes

Who have diabetes

Who have pre-existing heart disease

Who have pre-existing heart disease

Preparation for the test

The cardiac injury profile (maxi) test does not require any special preparations.

Interpretation of test results

Test name

Reference Range

Inference

 

Creatine Phosphokinase MB (CPK-MB)

 

 

Male: 55-170 units/L

Female: 30-135 units/L

(Normal reference range of serum CPK-MB is 3 to 5% of total CPK i.e. 5 to 25 IU/L)

Higher than normal levels indicate damage to the heart muscles

 

Myoglobin, Serum

 

 

 

25 to 72 ng/mL

High level: May be caused due to heart attack

Low level: May be caused due to conditions such as rheumatoid arthritis

                 

NT-pro BNP

 

 

 

100-300pg/ml

High levels indicate that the person suffers from heart failure

 

Troponin-I, High Sensitive (hsTnl)

 

·       0.5 mcg/L

 

·       0.6-2.3 mcg/L

 

 

·       >2.3 mcg/L

Normal

 

Weakly positive or suggestive of myocardial injury

Highly positive or suggestive of acute myocardial infarction

FAQs

How is the sample collected for the cardiac injury profile (maxi) test?

During this blood test, a healthcare professional will take a small amount of blood from a vein in your arm, using a needle, which is then collected in a test tube or vial. This process is usually completed within a few minutes.

Are there any risks associated with the cardiac injury profile (maxi) test?

There are no known risks. During a blood test, one may experience minor pain or bruising where the needle was inserted, but most symptoms will subside quickly.

What are the benefits of undergoing the cardiac injury profile (maxi) test?

This test yields important information about your heart health in a hassle-free manner, as it is a simple blood test. This test enables your healthcare provider to chart out an appropriate treatment plan for managing acute cardiac injury.

What is the turnaround time (TAT) for the cardiac injury profile (maxi) test?

The test results are made available within 24 hours of sample collection as this test yields critical information about a person’s heart health. Moreover, A rapid diagnosis is essential to save a person's life in the event of a heart attack.

What further tests might I require if I have an abnormal cardiac injury profile (maxi) test result?

If your levels of the cardiac injury profile (maxi) test are elevated, it may be necessary to conduct further tests to confirm the diagnosis and determine the appropriate treatment. Additional tests may involve imaging of your heart and an electrocardiogram (ECG).

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