Bone Health Profile
Bone Health Profile
A bone profile blood test also referred to as a bone metabolism or bone turnover marker test, is a diagnostic tool that evaluates various aspects of bone health and functionality. This test analyses specific markers in the blood to provide insights into bone turnover, mineral equilibrium, and overall bone metabolism. This profile typically involves various blood tests to assess levels of calcium, vitamin D, and other bone-related markers, to detect any abnormalities or fractures. The results provide valuable information regarding a person's risk of osteoporosis, fractures, and other bone-related conditions, guiding preventive measures and treatment strategies to promote optimal bone health and reduce the risk of debilitating bone disorders.
Thus, getting your bone health profile test done is recommended to prevent bone-related diseases
What tests are included?
Bone health profile measures the following parameters including:
Alkaline Phosphatase (ALP): This is an enzyme produced during bone formation by osteoblasts. Elevated ALP levels can indicate increased bone turnover, growth, or conditions like Paget's disease.
Calcium: This is a mineral that is important for bone health, nerve function, and muscle contraction. Deviations from normal calcium levels may signal conditions like osteoporosis, kidney issues, or hormonal imbalances.
C - reactive protein (CRP): This is a protein produced by the liver. Normally, blood contains low levels of C - reactive protein. The liver releases more CRP into your bloodstream when the body is inflamed.
Phosphate: This is a mineral that collaborates with calcium for bone health and is vital for energy production and cell function. Abnormal phosphate levels may indicate bone disorders or kidney dysfunction.
Creatinine: This is a waste product produced by your muscles as a result of routine metabolic activity. Higher levels of creatinine may be an indication of kidney disease.
Vitamin D: This vitamin is essential for bone health and calcium absorption. Vitamin D deficiency can weaken bones and increase fracture risk.
Complete blood count (CBC): This is a common blood test that can help detect a wide range of diseases like infections, anaemia, immune system disorders, and blood cancers.
Symptoms of problems in bone metabolism
Deformed bones
Low bone density (osteoporosis or osteopenia)
Abnormal bone development
Dental abnormality
Kidney stones
Muscle weakness or cramps
Rickets, a problem with bone growth in children
Chronic (long-term) medical conditions
Diseases of thyroid
Parathyroid disease
Malnutrition
Intestinal diseases
Certain types of cancers
What is the Bone Health Profile used for?
The bone health profile is performed:
For the early detection of bone disorders
To assess the bone health
To monitor the effectiveness of certain bone disorder treatments
Test preparation
No special preparation or fasting is required for this test. Please tell your healthcare provider if you are taking any medications or supplements before undergoing the test.
Interpretation of the Test Results
Interpretation of the results
|
Parameters |
Normal range |
|
Alkaline phosphatase (ALP) |
44 - 147 international units per litre |
|
Calcium |
8.5 to 10.2 milligrams per decilitre |
|
C-Reactive Protein (CRP), Quantitative |
0.5-3.0 milligrams per litre |
|
Phosphate, Serum |
2.5-4.5 milligrams per decilitre |
|
Creatinine, Serum |
0.7-1.3 milligrams per decilitre |
|
Vitamin D |
30 –100 nano grams per millilitre |
Reference ranges for complete blood count (CBC) test
|
Parameters |
Normal range |
|
RBC count (Male) |
4.7 to 6.1 million cells/ microliter |
|
RBC count (Female) |
4.2 to 5.4 million cells/ microliter |
|
WBC count |
4,500 to 10,000 cells/ microliter |
|
Hematocrit (Male) |
40.7% to 50.3% |
|
Hematocrit (Female) |
36.1% to 44.3% |
|
Hemoglobin (Male) |
13.8 to 17.2 grams per decilitre |
|
Hemoglobin (Female) |
12.1 to 15.1 grams per decilitre |
|
MCV |
80 to 95 femtoliter |
|
MCH |
27 to 31 picograms/cell |
|
MCHC |
32 to 36 grams per decilitre |
|
Platelet count |
150,000 to 450,000/decilitre |
Note: The normal ranges may vary depending on your age, gender, and diagnostic clinic.
Deviation from normal levels indicates the following:
· Abnormal levels of calcium, phosphate, creatinine, or vitamin D indicate bone mineral imbalances or underlying medical conditions such as kidney disorder, thyroid, etc.
· Elevated alkaline phosphatase levels indicate increased bone turnover rate or growth.
· Elevated CRP levels indicate inflammation of the bones.
· Abnormal levels of haemoglobin, haematocrit or RBCs can be signs of anaemia, heart disease, or iron deficiency.
· Low white blood cell count might be caused due to a bone marrow disorder, autoimmune disorder, or cancer.
FAQs
How is the sample collected for bone health profile?
A blood sample is collected from a vein in your arm using a small needle. Usually, this process does not take more than 5 minutes
What are the risks involved in bone health profile sample collection?
This test involves negligible risk. There might be slight pain or tenderness around the site where the needle went in. Rarely, the site can become infected
What is the turnaround time (TAT) for the results of the bone health profile?
The results of the bone health profile are usually available within 1-2 working days after sample collection. This duration may vary depending on the diagnostic clinic
How often should bone profile blood tests be done?
The recommended frequency for bone profile blood tests varies based on individual health factors and risk assessments. Your healthcare provider will advise you on the appropriate timing for testing and monitoring according to your specific needs
How can I reduce the risk of developing bone disorders?
To reduce the risk of developing bone disorders, focus on maintaining a balanced diet rich in calcium and vitamin D, essential for bone health. Engage in weight-bearing exercises regularly to strengthen bones and improve overall bone density. Avoid smoking and limit alcohol intake, as these habits can weaken bones. Regular check-ups with a healthcare provider can also help monitor bone health
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