Beta 2 Glycoprotein 1 Panel
Beta 2 Glycoprotein 1 Panel
Beta 2 glycoprotein 1 panel is used to identify beta-2 glycoprotein I IgA, IgG, & IgM antibodies in the blood. Beta 2 glycoprotein I antibodies are also known as antiphospholipid antibodies. These antibodies target the body’s own lipid proteins (phospholipids) located in the outer membrane of cells and platelets.
This panel helps in the diagnosis of antiphospholipid syndrome (APS), determining the cause of inexplicable blood clot formation, and the cause of recurrent miscarriages in women. It is usually ordered along with other tests such as lupus anticoagulant and cardiolipin antibody.
Thus, getting a beta 2 glycoprotein 1 panel done is recommended if you have any signs of excessive clotting or pregnancy complications such as preeclampsia, lupus, etc. to detect the presence of antiphospholipid antibodies in the blood
Symptoms of blood clots
A few common symptoms of blood clots include:
Chest pain
Shortness of breath
Seizures
Headache
Who should get tested?
The beta 2 glycoprotein 1 panel is recommended in individuals if they have:
Family history of antiphospholipid syndrome
Unusual blood clots in the veins and arteries
Stroke
Repeated miscarriages
Preeclampsia
Test preparation
No special preparation is required for a beta 2 glycoprotein 1 panel.
Please tell your healthcare provider if you have any medical condition or you are on any medications before taking the test
Interpretation of the Test Results
Interpretation of results
|
Parameters |
Normal Reference level |
|
Beta 2 glycoprotein IgA |
<=20.00 Standard IgA beta-2 glycoprotein Unit (SAU) |
|
Beta 2 glycoprotein IgG |
<=20.00 Standard IgG beta-2 glycoprotein Unit (SGU) |
|
Beta 2 glycoprotein IgM |
<=20.00 Standard IgM beta-2 glycoprotein Unit (SMU) |
Deviations from normal levels indicate the following:
· Low levels of antibodies (beta 2 glycoprotein I, IgA, IgG, IgM, serum < 20.00 SAU/SGU/SMU) demonstrate a low risk for blood clots.
· Elevated levels of antibodies (beta 2 glycoprotein I, IgA, IgG, IgM, serum > 20.00 SAU/SGU/SMU) are found in individuals with antiphospholipid syndrome (APS) and are associated with increased risk of thrombosis and/or pregnancy-related complications.
FAQs
How is the sample collected for a beta 2 glycoprotein 1 panel?
A blood sample is collected from a vein in your arm using a small needle. Usually, this process does not take more than 5 minutes
What are the risks associated with a beta 2 glycoprotein 1 panel?
This test involves negligible risk. There might be slight soreness or tenderness around the site where the needle was injected. Rarely, the site can become infected
What is the turnaround time (TAT) for the beta 2 glycoprotein 1 panel?
Beta 2 glycoprotein 1 panel test result is usually available within 2-6 working days after the sample collection. The duration may vary depending on the diagnostic clinic
Can certain medications affect my beta 2 glycoprotein I panel results?
Yes, medications such as propranolol, phenytoin, procainamide, chlorpromazine, quinine, amoxicillin, etc. could affect the accuracy of the beta 2 glycoprotein I panel results
What factors can increase the risk of blood clots if I have antiphospholipid antibodies?
Antiphospholipid antibodies increase your risk of developing blood clots if you:
· Become pregnant
· Are immobile for a long time
· Have surgery
· Smoke cigarettes
· Take estrogen therapy or oral contraceptives
Have high cholesterol levels
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