APO B: APO A-1 Ratio (Apolipoprotein B: Apolipoprotein A1 Ratio)

Apolipoproteins are proteins that bind to lipids in order to facilitate the transportation of cholesterol in the bloodstream. The two primary types of apolipoproteins that are typically assessed are apolipoprotein A and apolipoprotein B. Apolipoprotein A primarily associates with HDL (high-density lipoprotein), which is considered the "good" cholesterol, and plays a crucial role in removing harmful cholesterol from the blood. On the other hand, apolipoprotein B binds to LDL (low-density lipoprotein), known as the "bad" cholesterol, and contributes to the development of heart diseases by promoting the formation of plaques or the obstruction of arteries.

The Apo B: Apo A1 ratio test measures Apo-B/Apo-A ratio in the blood. Elevated Apo B: ApoA1 ratios indicate an increased risk of cardiovascular diseases, as it suggests a higher concentration of atherogenic particles (lipoprotein particles that lead to plaque formation) relative to protective ones.

This test offers insights into lipid metabolism, aiding in personalized risk assessment and treatment strategies for cardiovascular health. Monitoring and managing this ratio is crucial in preventive cardiology, in guiding interventions to maintain a favourable balance and to reduce the risk of atherosclerosis and related complications