ANA by Immunoblot
ANA by Immunoblot
The ANA by immunoblot test is used to detect antinuclear antibodies in the blood, which are responsible for attacking the nucleus of cells. By using the immunoblot technique, specific ANA antibodies can be identified. Elevated levels of ANA can indicate the presence of an autoimmune disorder. This test is valuable in diagnosing autoimmune conditions and ruling out diseases like lupus or other autoimmune disorders.
Therefore, getting the ANA by immunoblot test is recommended to prevent various immune-mediated complications
What is an ANA by Immunoblot test used for?
ANA by immunoblot test is used to diagnose autoimmune diseases like
Systemic lupus erythematosus (SLE)
Rheumatoid arthritis (Joints)
Scleroderma (Skin)
Sjogren's syndrome (Glands)
Addison Disease (Adrenal gland)
Autoimmune hepatitis (Liver)
Psoriasis (Skin)
Type 1 diabetes
Thyroid diseases (Autoimmune)
Who should get tested?
An ANA by immunoblot test is recommended to be performed on a regular basis for individuals who have symptoms of an autoimmune disease. The symptoms vary depending on the affected body part. The common symptoms include
Fever
Fatigue
Weight loss
Muscle or joint aches
Rashes
Recurrent sores
Hearing loss
Vision loss
Blood in urine
Abdominal pain
Test preparation
Ensure your doctor is aware of what prescription drugs, over-the-counter medicines, or dietary supplements you are taking. Ask your doctor for details about pre-test preparations, and make sure to follow instructions closely
Interpretation of the Test Results
Negative result
If your test results were negative, it indicates the absence of antinuclear antibodies in your blood. It means that you are less likely to have an autoimmune disease.
Positive result
If your test results were positive, it indicates the presence of antinuclear antibodies in your blood. It means that you are more likely to have an autoimmune disease
FAQs
How is the sample collected for an ANA by immunoblot test?
A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes
Are there any risks associated with an ANA by immunoblot test?
No, there are no associated risks with ANA by immunoblot test. It is a simple blood test that carries minimal risks, such as experiencing a slight sting or bruise at the needle insertion site
What is the turnaround time (TAT) for an ANA by immunoblot test?
ANA by immunoblot test results are usually available within 1-2 working days after the sample collection. This duration may vary depending upon the diagnostic clinic
How is ANA by immunoblot test different from other ANA tests?
The ANA by immunoblot utilizes immunoblot technology instead of the conventional ANA tests that rely on indirect immunofluorescence (IFA) to detect autoantibodies. This advanced approach offers a comprehensive and precise analysis of the antibodies implicated, enabling the precise identification of autoimmune conditions
Can a positive ANA test result be considered as a conclusive diagnosis of an autoimmune disease?
An autoimmune disease is not necessarily confirmed by a positive ANA result. Even individuals in good health can show positive ANA test results. Moreover, specific malignancies, drug usage, viral infections, etc. can also lead to a positive outcome. If your test is positive, your doctor may advise additional testing, especially if you continue to exhibit symptoms associated with an autoimmune condition
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