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Aldehyde Chopra Test For Kala Azar

Aldehyde Chopra Test For Kala Azar

The aldehyde test for kala azar is used to identify antibodies against the Leishmania parasite within the patient's blood.

Kala azar, also known as black fever, is a chronic and potentially life-threatening parasitic infection affecting the internal organs, including the liver, spleen, bone marrow, and lymph nodes. It is caused by the parasite Leishmania donovani.

Thus, it is recommended to get this test done for the timely diagnosis of kala azar. Early detection plays a pivotal role in the prompt management of the disease

Symptoms of kala azar

Persistent fever

Persistent fever

Fatigue

Fatigue

Drastic weight loss

Drastic weight loss

Swollen lymph nodes

Swollen lymph nodes

Excessive bleeding from wounds

Excessive bleeding from wounds

Enlarged liver and spleen

Enlarged liver and spleen

Recurrent infections caused by a weakened immune system

Recurrent infections caused by a weakened immune system

Who should get tested?

Individuals from endemic areas for kala azar who show appropriate clinical findings

Individuals from endemic areas for kala azar who show appropriate clinical findings

Individuals who have recently travelled to tropical locations

Individuals who have recently travelled to tropical locations

Individuals who have experienced a recent bug bite or undergone blood transfusions

Individuals who have experienced a recent bug bite or undergone blood transfusions

Test preparation

No special preparation is required for an aldehyde test for kala azar.

Interpretation of the Test Results

The test result may come as positive or negative.

Positive test results

Antibodies to a recombinant antigen specific for Visceral Leishmaniasis were detected. 

Negative test results

Antibodies to a recombinant antigen specific for Visceral Leishmaniasis were not detected

FAQs

How is the sample collected for an aldehyde test for kala azar?

A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes

What is the turnaround time (TAT) for aldehyde test for kala azar?

The test result is usually available within 3 working days after the sample collection. This duration may vary depending upon the diagnostic clinic

Are there any risks associated with the sample collection for the aldehyde test for kala azar?

This test involves negligible risk. There might be slight soreness or tenderness around the site where the blood is drawn. Rarely, the site can become infected

What are the limitations of the aldehyde test for Kala Azar?

False-positive results may be caused due to conditions like malaria. Additionally, assay interferences may be caused by the presence of viscous material or glycerol in the sample, as well as co-existing immunosuppressant conditions such as HIV

How is leishmaniasis transmitted?

Leishmaniasis is transmitted by the phlebotomine sand fly when it bites an individual or animal that is already infected, and subsequently bites another person, injecting them with the Leishmania parasite. Less common ways Leishmania can be transmitted include through sharing needles, through a blood transfusion, and from a pregnant woman to the fetus

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