Dual Marker (Double Marker) - First Trimester
Dual Marker (Double Marker) - First Trimester
The dual marker- first-trimester test is used to measure the concentrations of beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein A (PAPP-A) in the blood sample to determine the probability of a pregnant woman having a fetus with trisomy disorders such as Down syndrome.
Therefore, it is recommended for expectant mothers to get this test done to evaluate the potential risk of their baby having a chromosomal disorder.
What is the Dual Marker (Double Marker)- First Trimester test used for?
This test in pregnant women helps to identify the risk for
Trisomy 21 (Down syndrome)
Trisomy 18 (Edwards syndrome)
Who should get tested?
The test is offered to all pregnant women but should be especially done in women who
Have high maternal weight
Have advanced maternal age
Have insulin dependent diabetes mellitus
Have one or more than one fetus
Smoke
Preparation for test
No special preparation is required for the dual marker- first-trimester test.
Interpretation of results
Positive (abnormal result)
If the dual marker- first-trimester test result is abnormal, it might indicate a greater likelihood of chromosomal abnormalities such as Down syndrome and Edward’s syndrome. Nevertheless, it doesn't confirm the presence of a disorder. There is a need for further diagnostic testing, such as chorionic villus sampling (CVS) or amniocentesis to confirm diagnosis.
Negative (normal result)
If the dual marker- first-trimester test result is normal, it indicates a decreased likelihood of chromosomal abnormalities. It is important to note that it does not guarantee that the baby is free of abnormalities, but rather suggests a lower risk based on the screening.
FAQs
How is the sample collected for the dual marker - first-trimester test?
A blood sample is collected from a vein in your arm using a small needle. Usually, this procedure does not take more than 5 minutes.
What are the risks involved in the dual marker - first-trimester test?
This test involves negligible risk. There might be slight pain or tenderness around the site where the needle went in. Rarely, the site can become infected.
What is the turnaround time (TAT) for the results of the dual marker - first trimester test?
Results of the dual marker - first-trimester test are usually available within 48 hours after the sample collection. This duration may vary depending on the diagnostic clinic.
When is the dual marker - first-trimester test performed?
This test is typically done between the 11th and 14th weeks of pregnancy which provides an early indication of the likelihood of chromosomal abnormalities.
Can the dual marker - first-trimester test effectively predict the severity or prognosis of the abnormality?
The dual marker - first-trimester test cannot predict the severity or prognosis of the detected abnormality. This is a screening test that is used to assess the likelihood of chromosomal abnormalities, but it does not provide precise information about the severity or consequences of the abnormality on the unborn child or the long-term prognosis.
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