Beta 2 Glycoprotein I IgG
Beta 2 Glycoprotein I IgG
Beta-2 glycoprotein I IgG antibodies are the autoantibodies that are associated with blood clotting disorder. Improper blood clotting could be caused by the immune system mistakenly attacking one's own body cells, considering them as alien or foreign entities.
A beta-2 glycoprotein I IgG test detects and measures the levels of IgG antibodies in an individual’s blood. It is helpful in diagnosing the root cause of certain medical conditions such as recurrent miscarriages, antiphospholipid syndrome, etc.
Other names of beta-2 glycoprotein test are Anti-beta-2 glycoprotein 1, β2-glycoprotein 1 antibodies, Beta 2GP1 Ab
Symptoms of blood clotting
A few common symptoms of blood clots include:
Chest pain
Shortness of breath
Seizures
Headache
Who should get tested?
The beta 2 glycoprotein I IgG test is recommended in individuals if they have:
Family history of antiphospholipid syndrome
Unusual blood clots in the body veins and arteries
Stroke
Repeated miscarriages
Pre-eclampsia
Test preparation
No special preparations are required for beta-2 glycoprotein I IgG antibody testing. It is a simple blood test in which your healthcare provider will insert a small needle in a vein in your arm and collect a few mL of blood into a sterile test tube.
Please tell your healthcare provider if you are on any medications before taking the test
Interpretation of the Test Results
Normal range: <20 SGU (standard IgG beta-2 glycoprotein unit)
Deviations from the normal range:
- Greater than the normal range may increase the risk of blood clots in an individual’s blood.
- Increased blood clots in the individual’s system may lead to different medical conditions such as recurrent miscarriages in pregnant females, antiphospholipid syndrome, etc.
FAQs
What is the turnaround time (TAT) for beta-2 glycoprotein I IgG test?
The test results of beta-2 glycoprotein I IgG test are usually available within 6 -7 working days after the sample collection
Are there any risks associated with beta-2 glycoprotein I IgG test?
No, there are no associated risks with beta-2 glycoprotein I IgG test. It is a simple blood test and may involve negligible risks such as a feeling of slight sting or a bruise at the site of needle insertion. It usually resolves within a few minutes to a couple of hours. Rarely, the site can become infected
What are the other tests that identifies the possibility of antiphospholipid syndrome in an individual?
A few other tests in addition to beta-2 glycoprotein I IgG, that could help determine the possibility of the antiphospholipid syndrome include beta-2 glycoprotein I IgA and IgM
What medications can interfere with the test results of beta-2 glycoprotein I IgG test?
Certain medications such as phenytoin, propranolol, chlorpromazine, quinine, etc., can affect the test results of beta-2 glycoprotein I IgG antibody test.
I had two consecutive miscarriages in the last three years. Should I undergo beta 2 glycoprotein I IgG test?
Yes, if you've had two miscarriages in a row, you should get a beta 2 glycoprotein I IgG test. As the presence of beta 2 glycoprotein I IgG antibodies indicates the possibility of antiphospholipid syndrome (characterised by severe blood clots in the body's arteries and veins), it is thought that these clots may block blood supply to the placenta and result in miscarriages during the first trimester
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