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Apolipoprotein B Test

Apolipoprotein B Test

The apolipoprotein B test measures the level of Apo B, a protein associated with low-density lipoprotein (LDL) cholesterol. LDL cholesterol is considered "bad" because it deposits excess cholesterol in the tissues from the bloodstream. 

 

Thus, getting your apolipoprotein B test done can help in the early detection of cardiovascular disease risk, as high Apo B levels may indicate increased LDL function and an increased risk of heart disease. It can also be used for cholesterol monitoring and diagnosing a rare inherited apolipoprotein B (apo B) deficiency.

 

This test is also known as:

Apolipoprotein B-100, ApoB100, Apolipoprotein B, Apo B

Who Should Get Tested?

Apolipoprotein B test is recommended to be performed frequently in adults who are at risk of developing cardiovascular diseases. Examples of risk factors include

If you are over 60 years of age

If you are over 60 years of age

High cholesterol on a prior test

High cholesterol on a prior test

Past history of heart disease

Past history of heart disease

Family history of heart disease or of high cholesterol

Family history of heart disease or of high cholesterol

Being overweight

Being overweight

Smoking cigarettes

Smoking cigarettes

Having high blood pressure (hypertension)

Having high blood pressure (hypertension)

Alcohol consumption

Alcohol consumption

Having type 2 diabetes

Having type 2 diabetes

Eating an unhealthy diet

Eating an unhealthy diet

Leading an inactive lifestyle

Leading an inactive lifestyle

Taking medications for high cholesterol levels

Taking medications for high cholesterol levels

Test Preparation

No special preparation is required for an apolipoprotein B test. However, if other tests such as a cholesterol panel are ordered along with this test, then it is important to fast for 9 to 12 hours prior to sample collection.

Interpretation of Results

The units of measurement for the results are Milligrams per decilitre (mg/dL)

Normal levels of ApoB-100 in adults are less than 100 mg/dL.

Deviation from normal levels indicates the following:

·         Generally, an apolipoprotein B level less than 100 mg/dL is considered to be optimal.

·         High levels of Apolipoprotein B are generally considered harmful, as they are associated with a higher risk of cardiovascular diseases.  

Low levels of Apo B are associated with a decreased risk of cardiovascular diseases.

FAQs

How is the Apolipoprotein B test different from a standard cholesterol test?

While cholesterol tests focus on total, HDL, and LDL cholesterol, the apolipoprotein B test assesses a specific protein associated with LDL particles, providing a specific measure.

How is the sample collected for an apolipoprotein B test?

A blood sample is taken from a vein in the arm using a fine needle. This procedure typically takes no longer than five minutes.

What is the turnaround time (TAT) for the results of an apolipoprotein B test?

Apolipoprotein B test result is usually available within 24 hours, although it could take longer at times.

What are the risks associated with an apolipoprotein B test?

This test involves negligible risk. There might be slight bruising or tenderness around the site of needle insertion.

What might affect my apolipoprotein B test result?

The results of an apolipoprotein B test may be affected by factors such as the use of certain medications, alcohol consumption, and smoking. Additionally, stress and some medical conditions can also affect the accuracy of the test results. So, it is advised to consult your healthcare provider before undergoing the test.

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