Anti-ds DNA Antibody, ELISA
Anti-ds DNA Antibody, ELISA
The double stranded DNA antibody, ELISA test is a diagnostic test that detects the presence of autoantibodies in your blood. Autoantibodies are antibodies (proteins) that react with components of the body’s normal tissues and organs. Anti-ds DNA test helps in detecting and diagnosing systemic lupus erythematosus or SLE, a chronic inflammatory autoimmune condition. Higher levels of anti-dsDNA antibodies in the blood are an indication of a flare-up in lupus (sudden increase in disease symptoms).
Enzyme-linked immunosorbent assay or ELISA is an immunoassay method for the detection of DNA antibodies in the blood. This test helps to diagnose autoimmune systemic lupus erythematosus. Thus, getting your Anti-ds DNA Antibody, ELISA test is recommended to prevent various lupus-erythematosus-mediated complications such as reduced blood cell counts, constriction of blood vessels, and pneumonia (fluid accumulation in lung tissues), etc.
Symptoms of Systemic Lupus Erythematosus
Fever
Fatigue
Weight loss
Muscle or joint aches
Rashes
Recurrent sores
Hearing loss
Vision loss
Blood in urine
Abdominal pain
Cough
Numbness in different parts of the body
Chest pain
Skin rash (a butterfly rash)
Hair loss
Swollen lymph nodes
Who should get tested?
Anti-ds DNA Antibody, ELISA test is recommended in the following conditions:
To determine whether autoimmune symptoms caused are related to systemic lupus erythematosus or not
To detect the level of Anti-ds DNA antibodies in blood
To monitor an effective treatment plan for systemic lupus erythematosus
Test preparation
No preparation is required for the Anti-ds DNA Antibody, ELISA test.
Interpretation of the Test Results
The test result may come as positive or negative.
Positive result
If your test results were positive, it indicates the presence of the Anti-ds DNA Antibodies in your blood. A positive Anti-ds DNA Antibody test indicates that the individual is more likely to have an autoimmune systemic lupus erythematosus.
Negative result
If your test results were negative, it indicates the absence of the Anti-ds DNA Antibodies in your blood. It means that you are less likely to have an autoimmune systemic lupus erythematosus.
FAQs
How is Anti-ds DNA Antibody, ELISA test carried out?
A blood sample is used for this test. Blood is drawn with a needle from a vein in your hand or arm. The collected sample is then sent to the laboratory for analysis
Is there are any risk involved in Anti-ds DNA Antibody, ELISA test?
The Anti-ds DNA Antibody, ELISA test is a simple blood test procedure. When the needle pricks your arm or hand, you might experience a mild sting or pain. The area could be painful thereafter. Sometimes bruising, bleeding, infections, and dizziness may occur around the site of needle insertion.
How long should I wait for Anti-ds DNA Antibody, ELISA test results?
It depends on the testing laboratory. Anti-ds DNA Antibodies testing needs to be done with special tools and knowledge. Not every laboratory offers it. Your sample will generally be sent to a testing laboratory, where it may take several days before results are made available.
Should I be worried about positive Anti-ds DNA Antibody test results, during my pregnancy?
You don’t need to worry about positive test results. Women who have been diagnosed with lupus erythematosus can have a safe pregnancy. However, in some women, there will be complications related to pregnancy. So, seeking an expert opinion is advisable before this test.
What might affect my Anti-ds DNA Antibody test results?
Particular symptoms of a patient, personal, and medical history might affect your test results. The occurrence of irregular patterns of autoimmune disorders can also affect your test results. So, it is advisable to consult your healthcare provider soon after experiencing symptoms of an autoimmune disorder
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